{"id":"W3213921154","doi":"10.1158/1538-7445.panca21-po-039","title":"Abstract PO-039: Antiproliferative activity of inhibitors of RAD51, singly and in combination with chemotherapy drugs, against pancreatic cancer cell lines","year":2021,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Ontario Institute for Cancer Research; London Health Sciences Centre","funders":"","keywords":"Pancreatic cancer; RAD51; Cancer research; Cancer; Cancer cell; Chemotherapy; Cytotoxicity; Pharmacology; Chemistry; Homologous recombination; Medicine; Biology; Biochemistry; In vitro; Internal medicine; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001704903,0.000501389,0.0005470244,0.0005425347,0.0002210768,0.0003757381,0.0003395615,0.0003981478,0.005625481],"category_scores_gemma":[0.0001364478,0.0001972996,0.0004168247,0.0005161151,0.0002044896,0.0002463836,0.0002301317,0.001224157,0.001098424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002156799,"about_ca_system_score_gemma":0.0004264253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007461302,"about_ca_topic_score_gemma":0.001119271,"domain_scores_codex":[0.9998677,0.00002500584,0.00001741557,0.00002950511,0.00002987489,0.00003043961],"domain_scores_gemma":[0.9999163,0.00001742788,0.00001381059,0.00001214071,0.00001199132,0.00002824991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00312687,0.002447451,0.0006921061,0.0005288157,0.0000807393,0.0002698583,0.00006222157,0.0005669318,0.9529443,0.0002387789,0.003411532,0.03563038],"study_design_scores_gemma":[0.001214783,0.01645578,0.00818107,0.00005307218,0.0001538666,0.0007904046,0.00007599455,0.001865651,0.9554499,0.0001058908,0.015629,0.00002468797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9613227,0.01799214,0.001759922,0.0006917207,0.0005558147,0.0002713753,0.002799386,0.0006137664,0.01399322],"genre_scores_gemma":[0.9829264,0.005191422,0.00175605,0.0002800964,0.00007087953,0.0001552033,0.003130985,0.00003802935,0.006450911],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005625481,"threshold_uncertainty_score":0.01881915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02663913916150233,"score_gpt":0.3403880427483912,"score_spread":0.3137489035868889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}