{"id":"W3213949083","doi":"10.3389/fpsyt.2021.754969","title":"Neurofilament Light Chain Is a Promising Biomarker in Alcohol Dependence","year":2021,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Alcohol Consumption and Health Effects","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Alcohol dependence; Montreal Cognitive Assessment; Neuropsychology; Biomarker; Anxiety; Alcohol; Hyperintensity; White matter; Pittsburgh Sleep Quality Index; Medicine; Alcohol use disorder; Internal medicine; Mood; Psychiatry; Psychology; Magnetic resonance imaging; Cognition; Dementia; Disease; Chemistry; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003801861,0.00040044,0.0002863423,0.0009042245,0.0001965292,0.0003678176,0.0001943601,0.0004162992,0.001275913],"category_scores_gemma":[0.0006190243,0.00009704246,0.0001968088,0.0005821438,0.0001939496,0.0002812119,0.0002097377,0.0002843135,0.0002512261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001850182,"about_ca_system_score_gemma":0.0001045136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000545742,"about_ca_topic_score_gemma":0.0008381268,"domain_scores_codex":[0.9998823,0.00002720997,0.00001466741,0.00002977368,0.00003076347,0.00001526834],"domain_scores_gemma":[0.9995789,0.00006764985,0.0001974023,0.00001170999,0.00009113167,0.00005308803],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008945905,0.000142296,0.9552292,0.0001552492,0.0001470282,0.0001893467,0.00005301613,0.000156757,0.0217425,0.00004143385,0.0003065438,0.02094197],"study_design_scores_gemma":[0.00002441636,0.000775493,0.9874049,0.00004946065,0.0001526271,0.001142072,0.0001317439,0.001162258,0.007753692,0.0001983835,0.001193545,0.00001142862],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886106,0.008937524,0.0008953059,0.0001875763,0.00003107254,0.0000283078,0.0003525164,0.00003897103,0.0009180845],"genre_scores_gemma":[0.9972323,0.001283133,0.0008246752,0.00005891035,0.00002677898,0.000015674,0.0002171825,0.000002075499,0.0003393685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001275913,"threshold_uncertainty_score":0.004268408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0476769453691702,"score_gpt":0.3502637645173831,"score_spread":0.3025868191482128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}