{"id":"W3213949083","doi":"10.3389/fpsyt.2021.754969","title":"Neurofilament Light Chain Is a Promising Biomarker in Alcohol Dependence","year":2021,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Alcohol Consumption and Health Effects","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Alcohol dependence; Montreal Cognitive Assessment; Neuropsychology; Biomarker; Anxiety; Alcohol; Hyperintensity; White matter; Pittsburgh Sleep Quality Index; Medicine; Alcohol use disorder; Internal medicine; Mood; Psychiatry; Psychology; Magnetic resonance imaging; Cognition; Dementia; Disease; Chemistry; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003400176,0.0001767732,0.0003571995,0.0003470997,0.00005294621,0.00002082705,0.00008660024,0.0001631243,0.0002312225],"category_scores_gemma":[0.00006978108,0.0001797428,0.0000865218,0.0005913726,0.00003313645,0.00007563991,0.00003236952,0.0004126492,0.00005071992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001476005,"about_ca_system_score_gemma":0.0005377539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002588681,"about_ca_topic_score_gemma":0.0001114599,"domain_scores_codex":[0.9982748,0.0001333827,0.0004161561,0.0004798247,0.0002776516,0.0004181569],"domain_scores_gemma":[0.9992982,0.00001824936,0.00008196055,0.0003801112,0.00004145648,0.0001800288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002504006,0.0002659381,0.9118862,0.0005126905,0.00002817558,0.0002678674,0.00045887,0.000001473511,0.0006803217,0.00009041059,0.0764842,0.009073472],"study_design_scores_gemma":[0.004437382,0.0000844016,0.981774,0.000911224,0.0000495844,0.0001283649,0.000569878,0.002151394,0.0004597802,0.0006176294,0.008583216,0.0002331175],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9203016,0.01323317,0.001417029,0.04109187,0.01569599,0.001142693,0.000005695169,0.00007883617,0.007033139],"genre_scores_gemma":[0.9342964,0.0007867586,0.04151276,0.02174701,0.0002172947,0.00005044119,0.00002337787,0.00004615702,0.001319827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06988785,"threshold_uncertainty_score":0.7329699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0476769453691702,"score_gpt":0.3502637645173831,"score_spread":0.3025868191482128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}