{"id":"W3213958976","doi":"10.1182/blood-2021-147548","title":"An Open-Source Toolkit That Powers the Genome-Wide Analysis of Mature B-Cell Lymphomas (GAMBL) Project","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Spinal Cord Injury BC; Simon Fraser University","funders":"","keywords":"Exome; Genome; Computational biology; Biology; Lymphoma; Genomics; Exome sequencing; Bioinformatics; Gene; Genetics; Mutation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005911638,0.002621599,0.001491663,0.003271289,0.001181703,0.003403013,0.003457177,0.00143268,0.01584225],"category_scores_gemma":[0.009577018,0.001864753,0.003025603,0.002800568,0.0008985244,0.002483823,0.006693628,0.00313543,0.02357104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00107596,"about_ca_system_score_gemma":0.00320648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004867004,"about_ca_topic_score_gemma":0.006041317,"domain_scores_codex":[0.9978153,0.0004558927,0.0002256775,0.0008251341,0.0004910575,0.0001869983],"domain_scores_gemma":[0.9967474,0.001288815,0.0004015482,0.0006793069,0.0004323995,0.0004505738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00583553,0.0003061746,0.01904691,0.007118558,0.002356579,0.002312723,0.002943665,0.01287727,0.08742923,0.01672818,0.6627378,0.1803074],"study_design_scores_gemma":[0.001650257,0.0003753138,0.02858748,0.001507029,0.0008131982,0.001660545,0.0006601823,0.0736796,0.05427853,0.05211606,0.7839221,0.0007498194],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"software","genre_gemma":"software","genre_scores_codex":[0.007346886,0.001033613,0.2260707,0.000595041,0.0001932479,0.0005171488,0.1196596,0.6400242,0.004559606],"genre_scores_gemma":[0.0508994,0.001331965,0.4222493,0.001347465,0.0001023238,0.002847878,0.3896291,0.1258521,0.005740514],"genre_candidate":"software","genre_consensus":"software","teacher_disagreement_score":0.01584225,"threshold_uncertainty_score":0.05299765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01033080460477089,"score_gpt":0.245861853446118,"score_spread":0.2355310488413471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}