{"id":"W3213986007","doi":"10.1182/blood-2021-153691","title":"A Phase Ib Pilot Study of Itacitinib Combined with Alemtuzumab in Patients with T-Cell Prolymphocytic Leukemia (T-PLL)","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Prolymphocytic leukemia; Alemtuzumab; Medicine; Leukemia; Internal medicine; Oncology; Cancer research; Chronic lymphocytic leukemia; Transplantation","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001258262,0.001509953,0.002013607,0.0004887396,0.0004985777,0.001231341,0.0008864897,0.001225709,0.002702791],"category_scores_gemma":[0.000650997,0.000557474,0.001295017,0.0005950272,0.0008584997,0.0008812328,0.0004313202,0.003142984,0.001027265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001008489,"about_ca_system_score_gemma":0.001777562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001225339,"about_ca_topic_score_gemma":0.001968084,"domain_scores_codex":[0.999662,0.0001200355,0.00002209968,0.00006532713,0.00002652392,0.0001039569],"domain_scores_gemma":[0.9994045,0.00007842851,0.00007879624,0.00006059197,0.00004428583,0.0003333061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5641568,0.2147989,0.01251685,0.001377802,0.002055012,0.0009444887,0.0006282448,0.006204136,0.07385743,0.000408336,0.004336574,0.1187154],"study_design_scores_gemma":[0.3505085,0.6336662,0.007887972,0.00002740313,0.0004806765,0.0004027262,0.00006621716,0.001063499,0.003845583,0.0001241669,0.001903721,0.00002338538],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938334,0.001055136,0.0004463106,0.0002941922,0.00009277619,0.002426079,0.0006175652,0.00008127281,0.001153209],"genre_scores_gemma":[0.9940011,0.0007651427,0.001003486,0.0003650479,0.00009495846,0.001811125,0.001056953,0.00001853562,0.0008836578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002702791,"threshold_uncertainty_score":0.009041786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01614263831618313,"score_gpt":0.264765463696207,"score_spread":0.2486228253800238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}