{"id":"W3214205179","doi":"10.1182/blood-2021-145124","title":"The Echelon-2 Trial: 5-Year Exploratory Subgroup Analyses of a Randomized, Double-Blind, Phase 3 Study of Brentuximab Vedotin and CHP (A+CHP) Vs CHOP in Frontline Treatment of Pts with CD30-Positive Peripheral T-Cell Lymphoma","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Brentuximab vedotin; Subgroup analysis; Medicine; Internal medicine; Oncology; Exploratory analysis; Randomized controlled trial; Phases of clinical research; Clinical trial; Hodgkin lymphoma; Lymphoma; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007293547,0.002350077,0.005008328,0.0004753935,0.0003943496,0.001673664,0.001091806,0.001821574,0.004224344],"category_scores_gemma":[0.004980053,0.0006328859,0.007677433,0.0005731152,0.000718334,0.001559961,0.0008554466,0.002962922,0.0005312283],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008927275,"about_ca_system_score_gemma":0.0008127615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007205296,"about_ca_topic_score_gemma":0.00203325,"domain_scores_codex":[0.9971359,0.00192072,0.0001951642,0.0003771019,0.000160355,0.0002107081],"domain_scores_gemma":[0.9976879,0.0009469951,0.0005884387,0.0003257364,0.0001344261,0.000316467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.9677232,0.0007133484,0.00209016,0.001272374,0.02028196,0.00004760418,0.00004228677,0.0003661027,0.0008656481,0.0000871231,0.0005195747,0.005990546],"study_design_scores_gemma":[0.9228969,0.03090878,0.01115203,0.0002058704,0.03065366,0.0000866715,0.0001009525,0.001346872,0.0005108169,0.0007532812,0.001330015,0.00005433341],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9522288,0.03453878,0.002123504,0.001189997,0.001276415,0.00340762,0.003099599,0.0001517168,0.001983501],"genre_scores_gemma":[0.984794,0.003592721,0.001474258,0.001398618,0.0006612397,0.003496173,0.002532667,0.0000393564,0.002010851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007293547,"threshold_uncertainty_score":0.03857243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04121522537111414,"score_gpt":0.3278261193347301,"score_spread":0.2866108939636159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}