{"id":"W3214305505","doi":"10.1182/blood-2021-147095","title":"Impact of Tet2 Deficiency, and of <i>TET2</i> Mutations in Clonal Hematopoiesis, on Neutrophil/Granulocyte Immune Function","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Molecular biology; Haematopoiesis; Biology; Immune system; Granulocyte; Immunology; Bone marrow; Genetics; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001478871,0.0003496022,0.000234369,0.0002481302,0.0001323855,0.0003250052,0.0002299546,0.0004197773,0.00367657],"category_scores_gemma":[0.0001216952,0.0001189147,0.0002668623,0.0001040652,0.0003544445,0.0001486983,0.0002688491,0.0005619745,0.0004787995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002770123,"about_ca_system_score_gemma":0.000209018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007849771,"about_ca_topic_score_gemma":0.001609394,"domain_scores_codex":[0.9997932,0.00002923103,0.00002034879,0.00005969137,0.00005033632,0.00004716009],"domain_scores_gemma":[0.9998218,0.00003274744,0.00004887397,0.00001539251,0.00001215923,0.00006907581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003650118,0.00004077334,0.001074564,0.0000570186,0.00001411024,0.0001558926,0.00001350794,0.00008935101,0.996221,0.0001318191,0.0002083344,0.00162858],"study_design_scores_gemma":[0.00006143354,0.0008435255,0.02618865,0.00002906745,0.00009756479,0.001102159,0.00008109846,0.001343221,0.9640809,0.0001396524,0.006017893,0.00001477342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990884,0.001017206,0.002320252,0.0001728506,0.00006358443,0.00004854958,0.00283437,0.0001855552,0.002473573],"genre_scores_gemma":[0.9931464,0.000435671,0.001063431,0.0001555074,0.00001463489,0.00006552799,0.00139606,0.00007278156,0.003649887],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00367657,"threshold_uncertainty_score":0.01229936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0133212351521919,"score_gpt":0.2881665925666054,"score_spread":0.2748453574144135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}