{"id":"W3214487771","doi":"10.1101/2021.11.03.466838","title":"Wnt1-Cre mediated deletion of BMP7 suggests a role for neural crest-derived BMP7 in retina development and function","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"University of Alberta","keywords":"Retina; Biology; Cell biology; Anatomy; Noggin; Photopic vision; Electroretinography; Neuroscience; Bone morphogenetic protein; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000410056,0.0003860529,0.0004097435,0.0001675443,0.00007721509,0.00006682262,0.0001922653,0.0005268787,0.000007953185],"category_scores_gemma":[0.0003487655,0.000432919,0.00009290946,0.0002146403,0.00007856824,0.00001144906,0.0003145045,0.0002300635,0.00000130016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006071411,"about_ca_system_score_gemma":0.0006481356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003185177,"about_ca_topic_score_gemma":0.00005030146,"domain_scores_codex":[0.9979735,0.0001023666,0.0005403654,0.0008091595,0.0002077267,0.0003668556],"domain_scores_gemma":[0.9987217,0.0000300275,0.0003213239,0.0003933132,0.0004086276,0.0001250025],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003078751,0.00008940333,0.03218509,0.0003870109,0.00009140139,0.000006421154,0.00002805066,0.00005199103,0.96674,0.00001813471,0.00006245965,0.00003212367],"study_design_scores_gemma":[0.0009851083,0.0001290292,0.375805,0.0002151872,0.00004320396,3.523282e-8,0.00003536214,0.0002541268,0.6195107,0.000001693373,0.002514745,0.0005058586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952371,0.002650409,0.0009718114,0.00008574784,0.0002851043,0.0006955091,0.00003217368,0.00003411325,0.000008069809],"genre_scores_gemma":[0.9941103,0.0004657661,0.00486621,0.00008879254,0.00008800642,0.0002837066,0.00002981476,0.00006280323,0.000004595205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3472294,"threshold_uncertainty_score":0.9998122,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008452370459928216,"score_gpt":0.2071548613734504,"score_spread":0.1987024909135222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}