{"id":"W3214549902","doi":"10.25251/skin.5.supp.38","title":"Deucravacitinib Improves Psoriasis Symptoms and Signs Diary Domain Scores in Patients With Moderate to Severe Plaque Psoriasis: Results From the Phase 3 POETYK PSO-1 and POETYK PSO-2 Studies","year":2021,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research","funders":"Bristol-Myers Squibb","keywords":"Psoriasis; Plaque psoriasis; Medicine; Domain (mathematical analysis); Dermatology; Mathematics; Mathematical analysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007031973,0.0004205824,0.001222935,0.000142028,0.0001955796,0.0004469736,0.0002705276,0.0003853104,0.002500433],"category_scores_gemma":[0.0005600466,0.0001542036,0.0009887188,0.0001480978,0.0001925375,0.0003731112,0.0001116434,0.001017611,0.0003830872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003586783,"about_ca_system_score_gemma":0.0003446778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007656074,"about_ca_topic_score_gemma":0.00296471,"domain_scores_codex":[0.999765,0.00008926418,0.00002198572,0.00002994547,0.00004634251,0.0000475226],"domain_scores_gemma":[0.9996928,0.00008454864,0.00008587918,0.00002065993,0.00003558777,0.00008051162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.3308753,0.01209826,0.01373132,0.00266278,0.004387165,0.000197797,0.0001310731,0.001842764,0.05599901,0.0001710755,0.0140874,0.5638161],"study_design_scores_gemma":[0.3421811,0.3558112,0.2447053,0.0003352343,0.004590083,0.001832983,0.000199737,0.004015206,0.02142025,0.0004598938,0.02431395,0.0001350594],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9758747,0.018262,0.0003333506,0.0006358345,0.00016092,0.0002813432,0.0008183565,0.0001523074,0.003481277],"genre_scores_gemma":[0.9919568,0.005059625,0.0003649521,0.0004158592,0.00009035245,0.00008634417,0.000844555,0.00001397642,0.001167598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002500433,"threshold_uncertainty_score":0.008364797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01256961024483013,"score_gpt":0.2492058804157619,"score_spread":0.2366362701709317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}