{"id":"W3214549902","doi":"10.25251/skin.5.supp.38","title":"Deucravacitinib Improves Psoriasis Symptoms and Signs Diary Domain Scores in Patients With Moderate to Severe Plaque Psoriasis: Results From the Phase 3 POETYK PSO-1 and POETYK PSO-2 Studies","year":2021,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research","funders":"Bristol-Myers Squibb","keywords":"Psoriasis; Plaque psoriasis; Medicine; Domain (mathematical analysis); Dermatology; Mathematics; Mathematical analysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009594306,0.0004116403,0.0008657809,0.0001410777,0.0003575074,0.00002825924,0.0002932036,0.0001805812,0.00003364628],"category_scores_gemma":[0.0007894906,0.0001983731,0.00007217818,0.000277087,0.0004886913,0.0001193113,0.0001375328,0.0004460382,0.000005362914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006953942,"about_ca_system_score_gemma":0.0001237983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001666461,"about_ca_topic_score_gemma":0.0005121833,"domain_scores_codex":[0.9971234,0.001029314,0.0008471038,0.0003724025,0.0002084874,0.0004192675],"domain_scores_gemma":[0.9957091,0.002950677,0.0005125427,0.0003969019,0.0003330229,0.00009778814],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2118827,0.00315097,0.04568165,0.000215291,0.0222488,0.005128264,0.1850503,0.0002971019,0.1052373,0.0004291302,0.02378061,0.3968979],"study_design_scores_gemma":[0.3938657,0.05748229,0.1939192,0.01352458,0.01692885,0.03465561,0.149484,0.00005757867,0.0917818,0.02191124,0.02175646,0.004632632],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9680009,0.02527888,0.0000331946,0.00514745,0.0007293741,0.0004281066,0.0002931571,0.00001381858,0.00007507443],"genre_scores_gemma":[0.9929716,0.005358116,0.000215775,0.0007959519,0.0003072013,0.00001105622,0.00008419715,0.00003203387,0.0002240804],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3922653,"threshold_uncertainty_score":0.8089421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01256961024483013,"score_gpt":0.2492058804157619,"score_spread":0.2366362701709317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}