{"id":"W3214558823","doi":"10.1016/j.toxicon.2021.11.008","title":"Melittin administration ameliorates motor function, prevents apoptotic cell death and protects Purkinje neurons in the rat model of cerebellar ataxia induced by 3-Acetylpyridine","year":2021,"lang":"en","type":"article","venue":"Toxicon","topic":"Healthcare and Venom Research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Iran University of Medical Sciences","keywords":"Ataxia; Cerebellum; Cerebellar ataxia; Medicine; Purkinje cell; Apoptosis; Internal medicine; Motor coordination; Chemistry; Pharmacology; Neuroscience; Endocrinology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000462679,0.0001280691,0.000240665,0.00007141643,0.0000654703,0.00002588813,0.00007602158,0.000117252,0.00002946423],"category_scores_gemma":[0.0001999362,0.00009933559,0.00003700948,0.0002705573,0.0000294772,0.00007891894,0.00003832856,0.0003404221,0.000005535901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003965915,"about_ca_system_score_gemma":0.0005060418,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006885522,"about_ca_topic_score_gemma":0.00003411271,"domain_scores_codex":[0.9985739,0.000261369,0.0003164664,0.0002846667,0.0003146565,0.0002489557],"domain_scores_gemma":[0.9992664,0.0000832342,0.00008279448,0.0003201364,0.0001237455,0.0001236259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002984529,0.0004028787,0.002238621,0.0004569003,0.00001060718,0.00001676869,0.0003573418,0.000008712942,0.9936823,0.00004446704,0.0003867588,0.002096164],"study_design_scores_gemma":[0.001887963,0.002888827,0.01019283,0.0001730399,0.0000557957,0.00003282538,0.0006351417,0.006128213,0.9768454,0.0002501582,0.0007450833,0.0001646645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954736,0.0005268118,0.00009637862,0.002494094,0.00003404615,0.001029215,0.00002036568,0.00001416514,0.000311317],"genre_scores_gemma":[0.998399,0.0001712964,0.0001235789,0.0003626832,0.00005187826,0.00006725446,0.00005792456,0.00001775242,0.000748617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01683687,"threshold_uncertainty_score":0.4050788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06610561472033022,"score_gpt":0.3299832826052591,"score_spread":0.2638776678849288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}