{"id":"W3214589663","doi":"10.1182/blood-2021-154148","title":"A Phase II Study of CPX-351 Plus Venetoclax in Patients with Relapsed/Refractory (R/R) or Newly Diagnosed Acute Myeloid Leukemia (AML)","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Venetoclax; Medicine; Myeloid leukemia; Refractory (planetary science); Internal medicine; Leukemia; Chemotherapy regimen; Oncology; Azacitidine; Chemotherapy; Biology; Chronic lymphocytic leukemia","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001288848,0.0009225339,0.001433082,0.0003592435,0.0003450962,0.0006218546,0.0007085635,0.0006603103,0.002645417],"category_scores_gemma":[0.0006624713,0.000488056,0.0008443285,0.0003533918,0.0008129796,0.0005268579,0.0003404394,0.002141235,0.0005225529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007356384,"about_ca_system_score_gemma":0.001426463,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009603355,"about_ca_topic_score_gemma":0.001733148,"domain_scores_codex":[0.9996119,0.0001803367,0.00001868453,0.00008427422,0.00003142677,0.00007331843],"domain_scores_gemma":[0.9993181,0.0001047564,0.00009902352,0.00006810234,0.00003268337,0.0003773397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6986901,0.1535006,0.01350619,0.0006528211,0.0008507173,0.0003989276,0.0004994636,0.002220946,0.06216566,0.0002664915,0.001257833,0.06599024],"study_design_scores_gemma":[0.2608283,0.7179182,0.01535949,0.00001590396,0.0002984165,0.0002348198,0.00005966332,0.0007353408,0.003166913,0.00007220591,0.001292062,0.00001870431],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970797,0.0003543583,0.0002263643,0.00006257118,0.00003123001,0.001505343,0.0002370356,0.0000225333,0.0004807748],"genre_scores_gemma":[0.9949068,0.0005044532,0.001161792,0.0002065034,0.000103331,0.001422452,0.0006897175,0.00001039329,0.0009944527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002645417,"threshold_uncertainty_score":0.00884974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01673062602691864,"score_gpt":0.290518260808209,"score_spread":0.2737876347812904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}