{"id":"W3214605197","doi":"10.1182/blood-2021-147595","title":"Safety and Efficacy of Early-Start Deferiprone in Infants and Young Children with Beta-Thalassemia (START study)","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Deferiprone; Medicine; Chelation therapy; Deferoxamine; Thalassemia; Regimen; Beta thalassemia; Deferasirox; Pediatrics; Blood transfusion; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007345883,0.0004544556,0.001210744,0.0001283531,0.0001770012,0.0003635721,0.0003546028,0.0006006798,0.001519842],"category_scores_gemma":[0.0007248134,0.000202301,0.000740082,0.0001765856,0.000322629,0.0002260883,0.0002157967,0.001191543,0.0002081417],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000403105,"about_ca_system_score_gemma":0.0007143119,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001001848,"about_ca_topic_score_gemma":0.002509031,"domain_scores_codex":[0.9997515,0.000115916,0.00001797385,0.00003741238,0.00004284041,0.00003436675],"domain_scores_gemma":[0.9993099,0.0001593863,0.000185839,0.00003625775,0.00005960036,0.0002490126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.887783,0.01172085,0.025243,0.001286196,0.001404865,0.0002903306,0.0001897916,0.0004983124,0.009037957,0.0001101627,0.001578947,0.06085674],"study_design_scores_gemma":[0.3939607,0.4989639,0.09829389,0.0002420393,0.001664954,0.0005672896,0.0001276557,0.0004676434,0.002775346,0.00009941816,0.002809561,0.00002762534],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951507,0.003305921,0.00009128731,0.00009164626,0.00002640455,0.0002619431,0.000647924,0.00001443871,0.0004097625],"genre_scores_gemma":[0.9950153,0.002288131,0.0004921302,0.0002157474,0.00006168981,0.0004869747,0.0008204676,0.000004190708,0.0006153443],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001519842,"threshold_uncertainty_score":0.005084336,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006630251700912386,"score_gpt":0.2239705509040806,"score_spread":0.2173402992031682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}