{"id":"W3214693147","doi":"10.1002/hep.32230","title":"Immunomodulation and RNA interference alter hepatitis B virus–specific CD8 T‐cell recognition of infected HepG2‐NTCP","year":2021,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; Toronto Rehabilitation Institute; University of Toronto; University Health Network","funders":"","keywords":"Hepatitis B virus; TLR7; Cytotoxic T cell; Biology; T cell; CD8; HBsAg; Virology; Antigen; Interferon; Immunology; HBcAg; Immune system; Innate immune system; Toll-like receptor; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001033402,0.0002558571,0.000184285,0.0001382076,0.0001201335,0.0001856407,0.0001341273,0.0001722354,0.002057858],"category_scores_gemma":[0.00009939915,0.00009854466,0.0001920241,0.0000959268,0.0001833652,0.0001246122,0.0001096575,0.0004588471,0.0004630406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000167923,"about_ca_system_score_gemma":0.0001425737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000376408,"about_ca_topic_score_gemma":0.0005063603,"domain_scores_codex":[0.9998662,0.00002563523,0.00001408776,0.00002489941,0.00002425433,0.00004496579],"domain_scores_gemma":[0.9999244,0.00002053719,0.00001650178,0.000009847668,0.000009395627,0.00001936128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002463954,0.00005767723,0.00007775396,0.000020817,0.000002843359,0.00002229905,0.000008962797,0.00002512552,0.9989961,0.00002289861,0.00003229453,0.0004868996],"study_design_scores_gemma":[0.00003538511,0.0007421158,0.001948455,0.000003197185,0.00001342058,0.00009434948,0.00001828479,0.0004179004,0.9956801,0.00001146337,0.001032924,0.000002402633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973152,0.0003695319,0.0005394311,0.00004203154,0.00003784616,0.00002721525,0.0001978678,0.00003446221,0.001436351],"genre_scores_gemma":[0.9958856,0.000302795,0.0009084942,0.00005368701,0.00001942828,0.00007984068,0.0005037723,0.00001619806,0.002230103],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002057858,"threshold_uncertainty_score":0.006884217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03281732770039776,"score_gpt":0.2689295145356121,"score_spread":0.2361121868352144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}