{"id":"W3214760680","doi":"10.3390/curroncol28060411","title":"Screening for Colorectal Cancer Leading into a New Decade: The “Roaring ‘20s” for Epigenetic Biomarkers?","year":2021,"lang":"en","type":"review","venue":"Current Oncology","topic":"Colorectal Cancer Screening and Detection","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fundação para a Ciência e a Tecnologia","keywords":"Medicine; Epigenetics; Colorectal cancer; Cancer; Bioinformatics; Oncology; Computational biology; Internal medicine; Genetics; Biology; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006454307,0.0005264378,0.002251644,0.0002944318,0.000378338,0.00006028128,0.0002932374,0.0005745774,0.00005736542],"category_scores_gemma":[0.0007607898,0.0003914095,0.001207043,0.0006298792,0.000127709,0.00004508815,0.0001716824,0.000737883,0.000005882552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001260036,"about_ca_system_score_gemma":0.002741442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001639541,"about_ca_topic_score_gemma":0.0007184924,"domain_scores_codex":[0.9972672,0.000197075,0.0008004983,0.0008627591,0.0002246336,0.000647806],"domain_scores_gemma":[0.9970413,0.001571471,0.0005551055,0.0003260385,0.0002402455,0.0002658378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006733431,0.00005565094,0.00003598332,0.007726973,0.0006363488,0.000004480027,0.0002359385,0.000004122941,0.000008892443,0.00002543571,0.007385458,0.9832073],"study_design_scores_gemma":[0.001518895,0.002029625,0.00001822886,0.01249048,0.003879521,0.0001684248,0.0001056489,0.0004858962,0.00006733456,0.00004376179,0.9788123,0.0003798388],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001007991,0.9485775,0.04237165,0.0003498832,0.004507731,0.003820856,0.000043968,0.0001013051,0.0001263452],"genre_scores_gemma":[0.0001046519,0.9863374,0.004547548,0.00006641576,0.003559548,0.004594682,0.0002751157,0.0001206387,0.0003940478],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9828275,"threshold_uncertainty_score":0.9998538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2701950206733852,"score_gpt":0.5013922115894427,"score_spread":0.2311971909160575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}