{"id":"W3214764788","doi":"10.1371/journal.pone.0260522","title":"Treatment of necrotizing enterocolitis by conditioned medium derived from human amniotic fluid stem cells","year":2021,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Infant Nutrition and Health","field":"Nursing","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Necrotizing enterocolitis; Stem cell; LGR5; Amniotic fluid; Ileum; Stem cell factor; Andrology; Medicine; Amniotic epithelial cells; Immunology; Inflammation; Angiogenesis; Enterocyte; Apoptosis; Hypoxia (environmental); Internal medicine; Biology; Haematopoiesis; Small intestine; Chemistry; Adult stem cell; Embryonic stem cell; Fetus; Cancer stem cell; Biochemistry; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00003341399,0.0001467134,0.000438488,0.00005634379,0.0001797832,0.00003166161,0.00005615961,0.00008917561,0.0009661837],"category_scores_gemma":[0.000005979595,0.0001610278,0.00008492651,0.00008639024,0.00004814331,0.00007518809,0.00001555128,0.00007213359,0.00006836802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002153277,"about_ca_system_score_gemma":0.00003292815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003013795,"about_ca_topic_score_gemma":0.00008580749,"domain_scores_codex":[0.9986466,0.0001366203,0.0004031902,0.000266941,0.0002767575,0.0002699392],"domain_scores_gemma":[0.9992256,0.0001005841,0.00014139,0.0002565553,0.0001407644,0.0001351203],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007310489,0.002880997,0.001191485,0.0001745386,0.0001735393,0.00002992753,0.001255927,1.862422e-7,0.9929567,0.00004662416,0.00111331,0.0001036921],"study_design_scores_gemma":[0.002700972,0.0004903323,0.002394628,0.000355516,0.0001985732,0.000002905987,0.0004364339,0.0000450321,0.992502,0.0001190422,0.0006194469,0.0001351187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955701,0.0006313204,0.0000244585,0.001899862,0.0001782944,0.0004868769,0.0007429491,0.00007945214,0.0003867292],"genre_scores_gemma":[0.9970219,0.0001513317,0.000858365,0.0005654998,0.000179878,0.00005165765,0.0008229399,0.00002858751,0.0003198948],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002627867,"threshold_uncertainty_score":0.9999471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05251086106322883,"score_gpt":0.2690272899147976,"score_spread":0.2165164288515688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}