{"id":"W3214781451","doi":"10.1016/j.impact.2021.100369","title":"Dietary nanoparticles compromise epithelial integrity and enhance translocation and antigenicity of milk proteins: An in vitro investigation","year":2021,"lang":"en","type":"article","venue":"NanoImpact","topic":"Nanoparticles: synthesis and applications","field":"Materials Science","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Intestinal epithelium; In vitro; Caco-2; Nanotoxicology; Oxidative stress; Chemistry; Tight junction; Cell biology; Microbiology; Epithelium; Immunology; Biology; Toxicity; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003147637,0.0002671324,0.0002284808,0.0001083713,0.0001708306,0.0002426621,0.0001890583,0.0004347397,0.0006610507],"category_scores_gemma":[0.0002283921,0.0001767167,0.0002683311,0.00007540552,0.0002302113,0.0003257487,0.0002124907,0.0003850699,0.0001268137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003394826,"about_ca_system_score_gemma":0.0002138329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008386816,"about_ca_topic_score_gemma":0.001444916,"domain_scores_codex":[0.9998186,0.00004622331,0.000008331021,0.0000348237,0.00004509548,0.00004696349],"domain_scores_gemma":[0.9998466,0.00005408457,0.00003128348,0.00001570547,0.00003631489,0.00001597883],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002371022,0.00007576362,0.0001393847,0.00004775249,0.000005345805,0.00003362234,0.00002705173,0.00004145494,0.9983534,0.00004445944,0.00002051208,0.0009741648],"study_design_scores_gemma":[0.00001446698,0.001068812,0.001630752,0.000006279992,0.00002445037,0.00009972732,0.00007699108,0.0005973917,0.9954803,0.00004004226,0.0009579124,0.000002825156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968517,0.001189334,0.001332738,0.00007286711,0.00001760293,0.00001941922,0.00003454383,0.00000905164,0.000472727],"genre_scores_gemma":[0.9952034,0.0009749639,0.001571054,0.00006949208,0.00000897844,0.00001655132,0.00006209651,0.00001099893,0.002082434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008386816,"threshold_uncertainty_score":0.002463102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03156085481653607,"score_gpt":0.2836100963013281,"score_spread":0.252049241484792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}