{"id":"W3214960410","doi":"10.1038/s41523-021-00346-1","title":"The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group","year":2021,"lang":"en","type":"review","venue":"npj Breast Cancer","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":275,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Advancing Health Outcomes; University of British Columbia; Université de Montréal; Health Sciences Centre; Sunnybrook Health Science Centre; Princess Margaret Cancer Centre; BC Cancer Agency; University of Toronto; Ontario Institute for Cancer Research","funders":"Medical Research Council; National Cancer Institute; Cancer Research UK; National Institutes of Health; National Breast Cancer Foundation; National Center for Advancing Translational Sciences; Royal Australasian College of Physicians; National Health and Medical Research Council; Breast Cancer Research Foundation","keywords":"Oncology; Immunotherapy; Breast cancer; Medicine; Tumor-infiltrating lymphocytes; Biomarker; Internal medicine; Immune checkpoint; Cancer; Clinical Oncology; Triple-negative breast cancer; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001244775,0.0006374539,0.0009189878,0.002275849,0.0002570577,0.001147114,0.0005248054,0.001123425,0.001489731],"category_scores_gemma":[0.001712421,0.0002507714,0.000685345,0.002206463,0.0004387765,0.001494114,0.0008074913,0.002416136,0.0009443158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008020045,"about_ca_system_score_gemma":0.001896928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001877136,"about_ca_topic_score_gemma":0.00211467,"domain_scores_codex":[0.9997225,0.00005255611,0.00004138563,0.00005253041,0.0001028946,0.00002820938],"domain_scores_gemma":[0.9992398,0.0003479413,0.00006601661,0.00001490717,0.000274616,0.0000568488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001333498,0.00004430184,0.000323144,0.01302603,0.0000916249,0.0001764162,0.00009645407,0.0002610658,0.0009224604,0.003060279,0.07641988,0.905445],"study_design_scores_gemma":[0.00002309752,0.0001063263,0.001084429,0.005836705,0.0001871907,0.001122053,0.00006804113,0.00008218158,0.0004560154,0.001071427,0.9899408,0.00002175484],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000979199,0.9978726,0.00005548104,0.0009652462,0.0004499104,0.000003809664,0.00001925948,0.000003450066,0.0005323258],"genre_scores_gemma":[0.000665662,0.9976704,0.0001100225,0.0008701601,0.0002969746,0.000005685483,0.00003571344,0.000001486306,0.0003438781],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002275849,"threshold_uncertainty_score":0.006583035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0420120292087145,"score_gpt":0.3629201689834325,"score_spread":0.320908139774718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}