{"id":"W3215250616","doi":"10.1016/j.eururo.2021.11.008","title":"Not “If”, but “When” and “How”: Testing Antibody-Drug Conjugates in Patients with Non–muscle-invasive Bladder Cancer","year":2021,"lang":"en","type":"letter","venue":"European Urology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Bladder cancer; Drug; Cancer; Antibody; Antibody-drug conjugate; Urology; Internal medicine; Oncology; Pathology; Pharmacology; Immunology; Monoclonal antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002766644,0.0005311701,0.001053556,0.0004925409,0.002675552,0.001877275,0.0008189189,0.02856754,0.003606282],"category_scores_gemma":[0.01728749,0.0005197198,0.001042289,0.0004776685,0.001586574,0.002310013,0.0008749574,0.01487489,0.002498148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003568917,"about_ca_system_score_gemma":0.004099159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008427087,"about_ca_topic_score_gemma":0.01183942,"domain_scores_codex":[0.9971589,0.001302621,0.0004179774,0.000228539,0.0004984077,0.0003935992],"domain_scores_gemma":[0.9937296,0.003796838,0.0003747203,0.0001120701,0.000781081,0.001205637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003466072,0.0002169325,0.01043678,0.0001301311,0.00006127053,0.01254615,0.000423745,0.0002549027,0.001197047,0.002457801,0.9413477,0.03058091],"study_design_scores_gemma":[0.0007111224,0.0009978567,0.01623298,0.0008877869,0.0001747445,0.02720277,0.002114911,0.00355959,0.001221108,0.01912519,0.9275888,0.0001832385],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.002057141,0.0009574679,0.000120399,0.9887186,0.005191417,0.00001313977,0.0000485071,0.00001758693,0.002875704],"genre_scores_gemma":[0.02151093,0.001467158,0.0004878982,0.9487936,0.02278474,0.00003432561,0.00004904535,0.00002440024,0.004847838],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02856754,"threshold_uncertainty_score":0.0258944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01886378565327534,"score_gpt":0.244590630052256,"score_spread":0.2257268443989807,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}