{"id":"W3215295275","doi":"10.1016/j.xhgg.2021.100070","title":"Genetic factors associated with prostate cancer conversion from active surveillance to treatment","year":2021,"lang":"en","type":"article","venue":"Human Genetics and Genomics Advances","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Princess Margaret Cancer Centre; University of British Columbia; University Health Network","funders":"National Center for Advancing Translational Sciences; U.S. Department of Defense; National Heart, Lung, and Blood Institute; NorthShore University HealthSystem; National Cancer Institute; National Institutes of Health; Vanderbilt University","keywords":"Prostate cancer; Medicine; Cancer; Oncology; Internal medicine; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003502554,0.0002014616,0.0002177906,0.0004166778,0.0004426329,0.0006963986,0.0002925296,0.0004313276,0.001528915],"category_scores_gemma":[0.002434648,0.000139615,0.0004984458,0.0009873789,0.0003643894,0.0001579595,0.0002413791,0.0007686543,0.0001035176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002135273,"about_ca_system_score_gemma":0.0002302853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00430393,"about_ca_topic_score_gemma":0.004678786,"domain_scores_codex":[0.9995315,0.0001442821,0.00004406668,0.0001533414,0.0000729747,0.00005389697],"domain_scores_gemma":[0.9987412,0.0003457168,0.0005118283,0.000122835,0.00007739357,0.0002010862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005927921,0.00007627453,0.9877251,0.00003368522,0.0003778044,0.0006457036,0.0001588034,0.0002991873,0.004127979,0.000209475,0.0004889982,0.005264256],"study_design_scores_gemma":[0.00002129127,0.00007163101,0.997613,0.000009911068,0.0001164772,0.000902813,0.00006822164,0.0003700169,0.0001983434,0.0001982898,0.0004210166,0.000009108085],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980945,0.0006451108,0.0002381912,0.000178855,0.00001911499,0.000006899604,0.0003127345,0.00001385247,0.0004906504],"genre_scores_gemma":[0.9994874,0.0000942137,0.0001044278,0.0000426814,0.00001082145,0.000002255588,0.000155272,0.00000377878,0.00009898874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00430393,"threshold_uncertainty_score":0.008557737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03102467114616855,"score_gpt":0.3107104404903963,"score_spread":0.2796857693442277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}