{"id":"W3215353610","doi":"10.3389/fmed.2021.766689","title":"The Glomerular Endothelium Restricts Albumin Filtration","year":2021,"lang":"en","type":"review","venue":"Frontiers in Medicine","topic":"Chronic Kidney Disease and Diabetes","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Glycocalyx; Endothelium; Glomerular basement membrane; Chemistry; Albumin; Endothelial stem cell; Basement membrane; Cell biology; Immunology; Glomerulonephritis; Biochemistry; Biology; Endocrinology; Kidney; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005828375,0.0003184695,0.0006031311,0.0004081682,0.0003527387,0.001891622,0.0005818631,0.0008583218,0.00392974],"category_scores_gemma":[0.0007160317,0.0002720345,0.0004600671,0.0002236773,0.0006393376,0.0009844238,0.001131248,0.001575544,0.002059636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007610883,"about_ca_system_score_gemma":0.0007360571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00136497,"about_ca_topic_score_gemma":0.001005422,"domain_scores_codex":[0.999049,0.0001624083,0.00004852186,0.000204619,0.0003553022,0.0001801953],"domain_scores_gemma":[0.9993703,0.0001323168,0.00007360731,0.0001219957,0.0001749365,0.0001269183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005147462,0.0001319012,0.003147693,0.001110913,0.0001674838,0.001161992,0.000432744,0.0005083288,0.822984,0.03894377,0.01740587,0.1134905],"study_design_scores_gemma":[0.0001505885,0.0008637924,0.02395092,0.0004001395,0.0002234769,0.006600196,0.000447499,0.00633967,0.4707817,0.01906399,0.4710735,0.0001045874],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.5127749,0.19412,0.1363675,0.02033727,0.003679165,0.0002278342,0.001169114,0.00460273,0.1267215],"genre_scores_gemma":[0.9314458,0.02646216,0.01123054,0.003819526,0.00075808,0.00009697692,0.0005077831,0.000237537,0.02544164],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.00392974,"threshold_uncertainty_score":0.01314628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03142681012590012,"score_gpt":0.3322043682112945,"score_spread":0.3007775580853944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}