{"id":"W3215526355","doi":"10.1161/circ.144.suppl_1.13476","title":"Abstract 13476: ROR2 Deficiency is Associated With Endothelial Dysfunction and Reduced Angiogenesis in Pulmonary Arterial Hypertension","year":2021,"lang":"en","type":"article","venue":"Circulation","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Angiogenesis; Medicine; Pulmonary hypertension; Vascular remodelling in the embryo; Lung; Hypoxia (environmental); Endothelial stem cell; Wnt signaling pathway; Cancer research; Endothelial dysfunction; Adherens junction; Pathology; Vascular endothelial growth factor; Internal medicine; Cell biology; Signal transduction; Biology; Cell; Chemistry; Cadherin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001684265,0.0008217182,0.0005970655,0.0005427395,0.0002181778,0.0002763623,0.000292084,0.0007454732,0.006985368],"category_scores_gemma":[0.0001741577,0.0002106481,0.0002707255,0.00023402,0.000479427,0.0002110371,0.0002911052,0.0006121986,0.001576655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001477807,"about_ca_system_score_gemma":0.0001064523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002235762,"about_ca_topic_score_gemma":0.0001654288,"domain_scores_codex":[0.9997835,0.00004006395,0.00003317778,0.00006989583,0.00004683852,0.00002662271],"domain_scores_gemma":[0.9997637,0.00002895477,0.00009225734,0.00001619068,0.00001609658,0.00008285217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001264884,0.0001353159,0.001904249,0.00013744,0.00003917106,0.003230781,0.00002783961,0.00005372396,0.9905533,0.00009132507,0.0003052411,0.002256634],"study_design_scores_gemma":[0.0008773349,0.004009208,0.2441635,0.0001049427,0.0003478543,0.08450125,0.0001903713,0.00231029,0.6488008,0.0003708782,0.01426353,0.00006007307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937403,0.001625673,0.001689953,0.0002926265,0.00008584977,0.00003502597,0.00109362,0.0001224209,0.001314528],"genre_scores_gemma":[0.9883698,0.001000932,0.002176312,0.0001984662,0.0001366073,0.0001003161,0.001870395,0.00008150974,0.006065684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006985368,"threshold_uncertainty_score":0.02336836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03048422375155598,"score_gpt":0.2543060314193313,"score_spread":0.2238218076677753,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}