{"id":"W3215584091","doi":"10.1016/j.bbrep.2021.101174","title":"Wild type, dEX3 and 2B survivin isoforms localize to the tumor cell plasma membrane, are secreted in exosomes, and interact with extracellular tubulin","year":2021,"lang":"en","type":"article","venue":"Biochemistry and Biophysics Reports","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Brock University; Roswell Park Alliance Foundation, Roswell Park Cancer Institute; Roswell Park Cancer Institute; National Cancer Institute; National Institutes of Health; American Cancer Society","keywords":"Survivin; Microvesicles; Cell biology; Biology; Extracellular; Apoptosis; Chemistry; Biochemistry; microRNA; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008394039,0.0002844791,0.0001603017,0.0002498507,0.0001513001,0.0004965407,0.0001510196,0.0002382926,0.001355347],"category_scores_gemma":[0.0001452807,0.00009636303,0.0002304307,0.0002738068,0.0002071008,0.0002230473,0.0002195004,0.0003397477,0.0007538799],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003785442,"about_ca_system_score_gemma":0.0001666291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008125431,"about_ca_topic_score_gemma":0.0008403047,"domain_scores_codex":[0.9998581,0.00001627768,0.00002060384,0.00003865055,0.00004309128,0.00002310033],"domain_scores_gemma":[0.999882,0.00001176693,0.0000382176,0.0000185613,0.00001349892,0.00003598291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001207086,0.00001421611,0.001493049,0.00001479407,0.000006433255,0.0001421261,0.00001867192,0.00002006499,0.9968371,0.0001593851,0.00006107271,0.001112384],"study_design_scores_gemma":[0.00001653841,0.0001367755,0.02884025,0.000007537657,0.00001466748,0.002692574,0.0001280977,0.0006322542,0.9576306,0.0001332567,0.009758476,0.000009123044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920416,0.001058021,0.0036638,0.00009952633,0.00003975315,0.00001820711,0.001420105,0.00005913973,0.001599824],"genre_scores_gemma":[0.9892196,0.0006876288,0.002530978,0.00007022487,0.00000697755,0.000030124,0.002796669,0.00005164062,0.004606086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001355347,"threshold_uncertainty_score":0.004534125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004467076239328815,"score_gpt":0.1928310138230374,"score_spread":0.1883639375837086,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}