{"id":"W3215611204","doi":"10.3390/toxics9120324","title":"Cytotoxic and Transcriptomic Effects in Avian Hepatocytes Exposed to a Complex Mixture from Air Samples, and Their Relation to the Organic Flame Retardant Signature","year":2021,"lang":"en","type":"article","venue":"Toxics","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Environment and Climate Change Canada","funders":"","keywords":"Cytotoxicity; Partial least squares regression; Gene expression; Biology; Serial dilution; In vitro; Fire retardant; Gene; Mega-; Chemistry; Molecular biology; Toxicology; Genetics; Statistics; Mathematics; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000239104,0.0002670976,0.0002945718,0.00004244938,0.0001363877,0.00004868872,0.000239826,0.0001640361,0.0005597885],"category_scores_gemma":[0.0002365276,0.0001927728,0.00003810316,0.0004906956,0.00008109889,0.0001440453,0.0001842308,0.0003420136,0.00007386546],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002517364,"about_ca_system_score_gemma":0.00003383228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008880975,"about_ca_topic_score_gemma":0.004248178,"domain_scores_codex":[0.9984087,0.0002125867,0.0002386622,0.0005297095,0.0002304996,0.0003798343],"domain_scores_gemma":[0.9989896,0.0002517502,0.00004782857,0.0004474388,0.000002682077,0.00026072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004908376,0.00003053577,0.005001079,0.000005292984,0.00001541849,0.00003476701,0.006723496,0.00002760186,0.9776078,0.000008574408,0.0003510536,0.01014528],"study_design_scores_gemma":[0.0005676858,0.0001263395,0.80487,0.00005731106,0.00001808078,0.00004445526,0.0003116325,0.0006572816,0.1903945,0.0007660046,0.001919014,0.0002676367],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932423,0.0005103348,0.001402383,0.003530682,0.00009809746,0.0006640459,0.0004467097,0.00005279552,0.00005267939],"genre_scores_gemma":[0.9948869,0.00003732374,0.001780943,0.003105389,0.00005338993,0.000009229245,0.0000116818,0.00003806442,0.00007702897],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7998689,"threshold_uncertainty_score":0.7861047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01316418361242142,"score_gpt":0.2063618745634948,"score_spread":0.1931976909510734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}