{"id":"W3215705432","doi":"10.1093/neuonc/noab196.100","title":"STEM-26. BLOOD-TUMOR BARRIER IS COMPOSED OF MECHANOSENSING TUMOR CELLS THAT MASK THERAPEUTIC VULNERABILITY","year":2021,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Toronto; Hospital for Sick Children","funders":"","keywords":"Cell biology; Biology; Wnt signaling pathway; Stem cell; Signal transduction; Cancer research; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003039263,0.0002889575,0.001039016,0.0001258971,0.0001151437,0.000009415977,0.0001175823,0.0002266926,0.001417136],"category_scores_gemma":[0.00009865958,0.0002588468,0.0002644293,0.0003326589,0.0002662278,0.00005116965,0.0001157529,0.0006317974,0.0001078585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009615868,"about_ca_system_score_gemma":0.0007199484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001737746,"about_ca_topic_score_gemma":0.00001673593,"domain_scores_codex":[0.9971155,0.0009064515,0.0005763696,0.0006799047,0.0002799116,0.0004418816],"domain_scores_gemma":[0.997583,0.0008378283,0.0003039709,0.0007255001,0.0003136937,0.0002359656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006066204,0.0005975511,0.002112781,0.0001547417,0.0001227574,0.001229326,0.0004337316,0.000008861703,0.9897305,0.0000928963,0.00114375,0.003766534],"study_design_scores_gemma":[0.003253769,0.001984714,0.001683682,0.00003143016,0.0003705933,0.00135187,0.0005032842,0.0003061599,0.930196,0.0002078245,0.05992082,0.0001898214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917741,0.0002685447,0.0001238443,0.002369936,0.002225542,0.0004541617,0.00003610647,0.0001363271,0.002611449],"genre_scores_gemma":[0.9679678,0.00008710298,0.0007553833,0.03048411,0.0002600655,0.00001407897,0.00001701312,0.00006159173,0.0003528623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05953442,"threshold_uncertainty_score":0.9999864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04135974310705605,"score_gpt":0.2928577645974006,"score_spread":0.2514980214903446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}