{"id":"W3215705870","doi":"10.1093/neuonc/noab196.123","title":"CBIO-24. NF2 LOSS-OF-FUNCTION COOPERATES WITH HYPOXIA TO DRIVE RADIATION RESISTANCE IN GRADE 2 MENINGIOMAS","year":2021,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Radioresistance; Necrosis; Cancer research; Downregulation and upregulation; Gene knockdown; Biology; Clonogenic assay; DNA damage; Programmed cell death; Radiation therapy; Hypoxia (environmental); Pathology; In vitro; Cell culture; Medicine; Apoptosis; Internal medicine; Gene; Chemistry; Genetics; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001583821,0.0002996063,0.000331104,0.0003411402,0.0002410693,0.0004069853,0.0001774271,0.0002751841,0.001729188],"category_scores_gemma":[0.0001386486,0.0001253109,0.0003478082,0.000221591,0.0001851292,0.00009984078,0.0001496616,0.0004722832,0.0006114129],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004572721,"about_ca_system_score_gemma":0.0002480836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001696212,"about_ca_topic_score_gemma":0.0022585,"domain_scores_codex":[0.9998369,0.00001671392,0.00001667156,0.00003359718,0.00004644665,0.0000495185],"domain_scores_gemma":[0.9998473,0.00001638927,0.00004351842,0.00001875231,0.0000128113,0.00006124107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002317954,0.00004792377,0.001096359,0.0000344356,0.00001243277,0.0001346981,0.00001050349,0.00005925137,0.9973801,0.00003126305,0.0001581975,0.000802981],"study_design_scores_gemma":[0.00006532918,0.0007936553,0.06848411,0.00002262531,0.00005635252,0.001652478,0.0001354335,0.002469613,0.9192006,0.0001196059,0.006985866,0.00001435689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946556,0.001013286,0.0009928278,0.000159045,0.00003246669,0.00002861978,0.001922587,0.0001343624,0.001061106],"genre_scores_gemma":[0.994753,0.0003688605,0.0007152988,0.00009357616,0.000006708894,0.00003324343,0.002407732,0.00002617391,0.001595291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001729188,"threshold_uncertainty_score":0.00578469,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02078153122316179,"score_gpt":0.3060761352444582,"score_spread":0.2852946040212964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}