{"id":"W3215774559","doi":"10.1161/circ.144.suppl_1.12239","title":"Abstract 12239: Improvement in Measures of Disease Progression With Tafamidis in the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial (ATTR-ACT)","year":2021,"lang":"en","type":"article","venue":"Circulation","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Placebo; Internal medicine; Clinical trial; Transthyretin; Randomized controlled trial; Physical therapy; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001521545,0.0006809245,0.001472854,0.000184832,0.0002110378,0.0004938725,0.0002860542,0.0007220119,0.006646617],"category_scores_gemma":[0.0009651727,0.0001621036,0.0007168442,0.0002069481,0.0002921949,0.000313577,0.0001605307,0.001352624,0.0006486625],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002055745,"about_ca_system_score_gemma":0.0004761858,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003168925,"about_ca_topic_score_gemma":0.0008016542,"domain_scores_codex":[0.9996266,0.0002191299,0.00003093032,0.00004578177,0.00004130536,0.00003615328],"domain_scores_gemma":[0.9993371,0.0002199388,0.0001414987,0.00002900049,0.00007933456,0.0001930423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9517035,0.003022669,0.002880446,0.001321052,0.001064655,0.00006414105,0.00006239798,0.0003030342,0.008868471,0.00009591457,0.002492533,0.02812125],"study_design_scores_gemma":[0.820295,0.1480343,0.02514618,0.0001507436,0.001221845,0.0001610062,0.00002979588,0.00051893,0.001565529,0.0001511644,0.002706261,0.00001919341],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841393,0.007220456,0.0003931743,0.0006474711,0.0002166706,0.001836994,0.002079525,0.00007937822,0.003386973],"genre_scores_gemma":[0.9850394,0.002817935,0.001341026,0.000531513,0.0003751926,0.002741287,0.002362332,0.00001630152,0.004775039],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006646617,"threshold_uncertainty_score":0.0222351,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04076360592282999,"score_gpt":0.3319188279523115,"score_spread":0.2911552220294815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}