{"id":"W3215812855","doi":"10.1161/circ.144.suppl_1.14208","title":"Abstract 14208: Annexin A5 Inhibits Endothelial Inflammation Induced by Lipopolysaccharide-Activated Platelets and Extracellular Vesicles","year":2021,"lang":"en","type":"article","venue":"Circulation","topic":"Biomarkers in Disease Mechanisms","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Inflammation; Platelet; Extracellular vesicles; Lipopolysaccharide; Extracellular; Annexin; Cell biology; Platelet activation; Neutrophil extracellular traps; Annexin A5; Annexin A2; Vesicle; Extracellular vesicle; Immunology; Microvesicles; Biochemistry; microRNA; Flow cytometry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001658975,0.0003818388,0.0003946082,0.000261155,0.0001303899,0.0003215662,0.0002137626,0.0004877953,0.00719456],"category_scores_gemma":[0.000144946,0.0001060274,0.0002787566,0.000168613,0.0001452851,0.0002243317,0.0001984455,0.0007916171,0.0010263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001728486,"about_ca_system_score_gemma":0.0002720929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003143693,"about_ca_topic_score_gemma":0.0003304972,"domain_scores_codex":[0.9998786,0.00002513053,0.00001402252,0.00001776098,0.00003535698,0.00002901117],"domain_scores_gemma":[0.9999452,0.0000114224,0.00001085942,0.000003938197,0.000011673,0.00001692113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002927667,0.0005367685,0.000187848,0.0007304159,0.00008507969,0.0001606138,0.00004389541,0.0001988317,0.9759098,0.0005200423,0.002178275,0.01652085],"study_design_scores_gemma":[0.001135461,0.007302661,0.004179575,0.0001302388,0.0001257328,0.0006471737,0.0000593891,0.001380446,0.9648358,0.0002708747,0.01991474,0.00001808838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9529412,0.02478615,0.006388948,0.001001265,0.0007562711,0.0003126848,0.002377734,0.0006125393,0.01082318],"genre_scores_gemma":[0.9766915,0.006069604,0.003520498,0.0004805552,0.0001167704,0.0002290468,0.002910353,0.00003730915,0.009944359],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00719456,"threshold_uncertainty_score":0.02406818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01531875435564348,"score_gpt":0.2260305931636426,"score_spread":0.2107118388079991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}