{"id":"W3215812855","doi":"10.1161/circ.144.suppl_1.14208","title":"Abstract 14208: Annexin A5 Inhibits Endothelial Inflammation Induced by Lipopolysaccharide-Activated Platelets and Extracellular Vesicles","year":2021,"lang":"en","type":"article","venue":"Circulation","topic":"Biomarkers in Disease Mechanisms","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Inflammation; Platelet; Extracellular vesicles; Lipopolysaccharide; Extracellular; Annexin; Cell biology; Platelet activation; Neutrophil extracellular traps; Annexin A5; Annexin A2; Vesicle; Extracellular vesicle; Immunology; Microvesicles; Biochemistry; microRNA; Flow cytometry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000193734,0.0001802979,0.0001873311,0.00008650873,0.0001836322,0.00004830894,0.00007197267,0.0003869409,0.0005325651],"category_scores_gemma":[0.0001330007,0.0002011394,0.00005139982,0.0001159844,0.00006191998,0.0002795842,0.00004565863,0.0002051924,0.000162865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000604029,"about_ca_system_score_gemma":0.00006363241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003656145,"about_ca_topic_score_gemma":0.000006012099,"domain_scores_codex":[0.9988437,0.000141757,0.0003268923,0.0003800917,0.00006323162,0.0002443337],"domain_scores_gemma":[0.999386,0.00008041576,0.0001734397,0.0002286545,0.00009273662,0.00003880237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007237864,0.00005443331,0.0005866871,0.00002720869,0.0000877644,0.0000118751,0.0001969837,0.000005069063,0.9740777,0.0005120897,0.0001284209,0.02423938],"study_design_scores_gemma":[0.001016346,0.00001347506,0.02659288,0.00004104448,0.00003264111,0.00004312793,0.0001115248,0.00004637245,0.9703773,0.0009134461,0.0006037633,0.0002080546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965341,0.001847399,0.0004250769,0.0001758249,0.0004430872,0.000230143,0.00005285295,0.0001159381,0.0001755892],"genre_scores_gemma":[0.9990042,0.00002893597,0.00006518461,0.00004012151,0.00004925268,0.00001722803,0.00069937,0.00002473341,0.00007094281],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0260062,"threshold_uncertainty_score":0.8202227,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01531875435564348,"score_gpt":0.2260305931636426,"score_spread":0.2107118388079991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}