{"id":"W3215818615","doi":"10.1038/s41591-021-01590-5","title":"Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021","year":2021,"lang":"en","type":"review","venue":"Nature Medicine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":368,"is_retracted":false,"has_abstract":false,"ca_institutions":"AIDS Vancouver; Simon Fraser University; Queen's University; Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Medical Research Council; Institut National de la Santé et de la Recherche Médicale; Deutsche Forschungsgemeinschaft; National Research Foundation; National Institutes of Health; U.S. Department of Health and Human Services; Sidaction; International AIDS Vaccine Initiative; National Health and Medical Research Council; Bill and Melinda Gates Foundation; Delaney AIDS Research Enterprise","keywords":"Pandemic; Human immunodeficiency virus (HIV); Medicine; Clinical trial; Optimism; Virology; Immunology; Coronavirus disease 2019 (COVID-19); Disease; Psychology; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.002236566,0.0003925268,0.001293268,0.0002354277,0.0005602764,0.0001092538,0.0008596846,0.001599264,0.00236197],"category_scores_gemma":[0.0005554285,0.0002602961,0.0004857355,0.0008429083,0.001321156,0.0001015955,0.0002299848,0.002694134,0.0003971875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005373872,"about_ca_system_score_gemma":0.00225916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003409215,"about_ca_topic_score_gemma":0.00006764677,"domain_scores_codex":[0.9966263,0.0007173523,0.0004894414,0.0009549109,0.0004019152,0.0008100923],"domain_scores_gemma":[0.9973981,0.0006382167,0.0001277406,0.0006379316,0.00108556,0.000112427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002287885,0.0001326014,0.00001030933,0.001362969,0.001004064,0.00002963,0.00008161169,4.35636e-8,0.00002871468,0.004008315,0.3496709,0.643648],"study_design_scores_gemma":[0.001340489,0.0006259339,0.000006292248,0.00410455,0.0002889179,0.0001332616,0.0005460342,4.908715e-7,0.00001463111,0.0001960183,0.9925583,0.0001850934],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001966128,0.9894294,0.00003059554,0.0007206445,0.003569633,0.001048811,0.002491607,0.00002995471,0.002659731],"genre_scores_gemma":[0.0001307839,0.9454232,0.0001753616,0.00003655452,0.001157353,0.0002633414,0.02676472,0.00002866219,0.02602003],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6434629,"threshold_uncertainty_score":0.9999849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1094348316679624,"score_gpt":0.4856932708425364,"score_spread":0.376258439174574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}