{"id":"W3216121419","doi":"10.1101/2021.10.26.465878","title":"Chromosome-scale assemblies of Acanthamoeba castellanii genomes provide insights into Legionella pneumophila infection-related chromatin re-organization","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Dalhousie University","funders":"Fondation pour la Recherche Médicale; Agence Nationale de la Recherche; Dalhousie University; Natural Sciences and Engineering Research Council of Canada; European Commission; Gordon and Betty Moore Foundation","keywords":"Biology; Legionella pneumophila; Genome; Gene; Legionella; Amoeba (genus); Genetics; Microbiology; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000359265,0.000669377,0.0007531606,0.0003676714,0.0002833617,0.0002369726,0.0006090197,0.001174532,0.00004458939],"category_scores_gemma":[0.0003007814,0.0007104654,0.0002402651,0.001023807,0.0002974651,0.00003318264,0.001154471,0.0006965166,0.00002654756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001949513,"about_ca_system_score_gemma":0.001554727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003863966,"about_ca_topic_score_gemma":0.00008935229,"domain_scores_codex":[0.9963375,0.0002876524,0.0009068364,0.001348784,0.0005635237,0.0005556869],"domain_scores_gemma":[0.9960821,0.00003687221,0.0006867413,0.001497917,0.001410659,0.0002856897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000022141,0.0002252584,0.0212307,0.0008028367,0.000375299,0.00004636067,0.0001027624,0.0003295925,0.976492,0.00003603648,0.0003328631,0.000004163528],"study_design_scores_gemma":[0.0005264985,0.00015669,0.03154298,0.0003696215,0.0001134981,2.978486e-7,0.00002692698,0.0001667998,0.9630231,0.000002791052,0.003312155,0.0007587048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930929,0.004566026,0.0003674212,0.0001984274,0.0007758854,0.0007913127,0.00004034485,0.0001193674,0.00004831329],"genre_scores_gemma":[0.993136,0.005122681,0.0007353082,0.00007102257,0.0005829328,0.00008409818,0.00002767186,0.0002006953,0.00003957696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01346895,"threshold_uncertainty_score":0.9995347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01008200653119367,"score_gpt":0.2275779691638863,"score_spread":0.2174959626326927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}