{"id":"W3216184792","doi":"10.1038/s41598-021-02927-3","title":"Prenatal administration of IL-1Ra attenuate the neurodevelopmental impacts following non-pathogenic inflammation during pregnancy","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Preterm Birth and Chorioamnionitis","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Fonds de Recherche du Québec - Santé; Centre hospitalier universitaire Sainte-Justine; Hospital for Sick Children; Université de Montréal; Canadian Institutes of Health Research; McGill University Health Centre; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada; McGill University","keywords":"Inflammation; Astrogliosis; Dentate gyrus; Pregnancy; Medicine; Prenatal stress; Fetus; Placenta; Endocrinology; Myelin; Internal medicine; Immunology; Hippocampus; Biology; Central nervous system; Gestation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003267749,0.000120824,0.0001737174,0.00007693701,0.000268982,0.0001206536,0.0000652642,0.00005128018,0.00005044866],"category_scores_gemma":[0.0002940484,0.00009472224,0.0001588619,0.0003748588,0.00007386806,0.0002757486,0.00007387566,0.0001188097,0.000007629435],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004702128,"about_ca_system_score_gemma":0.0006392188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004051356,"about_ca_topic_score_gemma":0.00002002321,"domain_scores_codex":[0.9981726,0.00003651024,0.0005478908,0.0004280855,0.0005641149,0.000250778],"domain_scores_gemma":[0.9987966,0.00001709621,0.0003020522,0.0005990158,0.0001666229,0.0001186045],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003688628,0.00004972615,0.04451346,0.0003214043,0.00005606886,0.007138168,0.00103981,0.00000483621,0.9425631,0.000004282524,0.0001360837,0.004136172],"study_design_scores_gemma":[0.0003335485,0.0000415275,0.2372647,0.0007905593,0.00005984459,0.003974088,0.000123673,0.00004457623,0.7569905,0.000110337,0.0001682192,0.00009847236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952868,0.0002320385,0.00002737675,0.0002310923,0.002974104,0.0003500861,0.000006177248,0.00003261827,0.0008596974],"genre_scores_gemma":[0.9979945,0.00001419343,0.0002045923,0.00001036923,0.00007851786,0.00002135869,0.0002153958,0.00001272528,0.001448317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1927512,"threshold_uncertainty_score":0.3862661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009966249268268074,"score_gpt":0.2459191657716765,"score_spread":0.2359529165034084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}