{"id":"W3216302305","doi":"10.1101/2021.11.25.470064","title":"MTSviewer: a database to visualize mitochondrial targeting sequences, cleavage sites, and mutations on protein structures","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill Genome Centre; Montreal Neurological Institute and Hospital; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Mitochondrion; Biology; Cleavage (geology); Computational biology; Proteome; Genetic code; Mitochondrial DNA; Genetics; Database; Cell biology; Gene; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001983964,0.00347089,0.002154501,0.00322481,0.0007879245,0.002590446,0.004402948,0.001606116,0.05814319],"category_scores_gemma":[0.004770149,0.001818248,0.001991523,0.002459785,0.0005536463,0.002900769,0.004159729,0.002229658,0.04294256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009563076,"about_ca_system_score_gemma":0.001641538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00333468,"about_ca_topic_score_gemma":0.004136008,"domain_scores_codex":[0.9992544,0.0001225094,0.00009900418,0.0002271263,0.0002064755,0.00009053089],"domain_scores_gemma":[0.9986069,0.0005371745,0.0002159014,0.0002553691,0.0001954111,0.0001892499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001764235,0.000107501,0.003396945,0.004608822,0.0004515504,0.0009167065,0.0005015215,0.005718678,0.02238338,0.007135233,0.8559216,0.09709398],"study_design_scores_gemma":[0.001338693,0.0002661774,0.007548796,0.001132687,0.0003841683,0.001848044,0.0003336912,0.05312108,0.05927093,0.03107046,0.843169,0.0005162302],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"software","genre_gemma":"software","genre_scores_codex":[0.009381347,0.002507188,0.1195557,0.0005067135,0.0002491641,0.000280688,0.2894867,0.570582,0.007450462],"genre_scores_gemma":[0.05309312,0.002876307,0.1882707,0.0006404067,0.00009374071,0.001443095,0.631038,0.113303,0.009241643],"genre_candidate":"software","genre_consensus":"software","teacher_disagreement_score":0.05814319,"threshold_uncertainty_score":0.1945083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01565997475799769,"score_gpt":0.2553918169732597,"score_spread":0.239731842215262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}