{"id":"W3216507911","doi":"10.3390/molecules26237218","title":"Transporter Protein-Guided Genome Mining for Head-to-Tail Cyclized Bacteriocins","year":2021,"lang":"en","type":"article","venue":"Molecules","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Mount Royal University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Bacteriocin; Genome; Gene; Biology; Computational biology; Antimicrobial peptides; Whole genome sequencing; Peptide; Genetics; Biochemistry; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004151477,0.000711066,0.001153051,0.00194648,0.0004177707,0.001132852,0.000647514,0.0004971554,0.0009462165],"category_scores_gemma":[0.001257352,0.00022383,0.0009822657,0.002519114,0.0001933643,0.0004840934,0.0006300819,0.0005648442,0.0006985288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003697029,"about_ca_system_score_gemma":0.00099606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00153743,"about_ca_topic_score_gemma":0.002656593,"domain_scores_codex":[0.9997228,0.00004650569,0.00002274206,0.0000980995,0.00006208981,0.00004778968],"domain_scores_gemma":[0.9996446,0.0001151563,0.00008980337,0.00002827543,0.00008132905,0.00004081568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007645466,0.0004658338,0.02264745,0.001210662,0.0001484668,0.001115717,0.0003903449,0.006579813,0.8699302,0.0009588107,0.001465428,0.09432278],"study_design_scores_gemma":[0.0002933705,0.002719962,0.1807343,0.0004327027,0.001254945,0.007109638,0.003909003,0.2165716,0.5332514,0.004352499,0.04914749,0.0002230132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8860364,0.003210504,0.09089591,0.0006247801,0.00004822986,0.0006936532,0.01435084,0.001483563,0.002656054],"genre_scores_gemma":[0.703358,0.002464548,0.2463463,0.0002110867,0.00003024997,0.0003864652,0.04460417,0.0003850353,0.002214193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00194648,"threshold_uncertainty_score":0.003165424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02289402713824994,"score_gpt":0.2667357338235949,"score_spread":0.2438417066853449,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}