{"id":"W3216542016","doi":"10.3390/antibiotics10121443","title":"New Auranofin Analogs with Antibacterial Properties against Burkholderia Clinical Isolates","year":2021,"lang":"en","type":"article","venue":"Antibiotics","topic":"Plant Pathogenic Bacteria Studies","field":"Agricultural and Biological Sciences","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Cystic Fibrosis Canada","keywords":"Burkholderia cenocepacia; Burkholderia; Microbiology; Burkholderia cepacia complex; Biology; Antimicrobial; Antibiotics; Auranofin; Bacteria; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001605435,0.000223276,0.000393876,0.000007886436,0.0002003589,0.0001671097,0.0002161206,0.0001521378,0.0001300084],"category_scores_gemma":[0.0000893297,0.00007961537,0.0001168021,0.0002911963,0.0001250497,0.0001477352,0.0001504387,0.0001490734,0.00006778755],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000102093,"about_ca_system_score_gemma":0.00006646929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004909652,"about_ca_topic_score_gemma":0.0006526762,"domain_scores_codex":[0.9985552,0.0001191507,0.000375502,0.000442597,0.0001285675,0.0003789586],"domain_scores_gemma":[0.9993817,0.000112336,0.0001198582,0.0001099048,0.0001349103,0.0001413548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00008687611,0.00009464873,0.04331398,0.00001058655,0.00008413531,0.00008095268,0.00003900287,5.883068e-7,0.9437863,0.00007146778,0.001992162,0.01043936],"study_design_scores_gemma":[0.0009242391,0.0007420129,0.6254613,0.0002387117,0.0001243708,0.0001419124,0.0004434818,0.00005327996,0.3022616,0.00008467228,0.06871152,0.0008128585],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961259,0.0002866431,0.00001216382,0.00164785,0.0004537646,0.0001240995,0.00006314628,0.0001017399,0.001184744],"genre_scores_gemma":[0.9959057,0.0006219357,0.001048043,0.0005494189,0.0008446394,1.622108e-7,0.000166801,0.000002607655,0.0008607054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6415247,"threshold_uncertainty_score":0.3246621,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04005267790727453,"score_gpt":0.23161156261304,"score_spread":0.1915588847057655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}