{"id":"W3216605774","doi":"10.1016/j.celrep.2021.110071","title":"Heterogeneity of human anti-viral immunity shaped by virus, tissue, age, and sex","year":2021,"lang":"en","type":"article","venue":"Cell Reports","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; National Cancer Institute; National Science Foundation; National Institutes of Health; Canadian Institutes of Health Research; Leona M. and Harry B. Helmsley Charitable Trust; American Autoimmune Related Diseases Association; National Center for Research Resources; Cancer Research Institute","keywords":"Biology; Immune system; Immunity; Virus; Immunology; Virology; CD8","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001750736,0.0001368473,0.000278284,0.00004392007,0.0001817673,0.00001662199,0.00005089102,0.0001857322,0.00174689],"category_scores_gemma":[0.00003547721,0.0001387693,0.00007125522,0.00006213861,0.000128121,0.0000866811,0.0001011155,0.0002455707,0.00003823119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001766405,"about_ca_system_score_gemma":0.00002799398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004022442,"about_ca_topic_score_gemma":0.00002356773,"domain_scores_codex":[0.9989204,0.0001634096,0.0004312478,0.0002728209,0.00003277558,0.0001793468],"domain_scores_gemma":[0.9992433,0.00002813919,0.000257256,0.0003783914,0.00007322145,0.000019714],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001076103,0.0002010689,0.003221573,0.00002578494,0.00005273559,0.000156176,0.0001489881,2.92844e-7,0.981614,0.000006920035,0.01402796,0.0005337318],"study_design_scores_gemma":[0.0002505164,0.00009224077,0.005686922,0.00001043742,0.00002840287,0.0004294661,0.0001313115,4.989838e-7,0.851966,0.00001947171,0.1412721,0.0001126274],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871489,0.004216903,0.00004216416,0.00001342857,0.001520367,0.00008802068,0.000003574778,0.00003859245,0.006928009],"genre_scores_gemma":[0.9500033,0.0001880649,0.00001258145,0.00008762669,0.00001186911,0.000003834145,0.0004747355,0.00001299714,0.04920502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.129648,"threshold_uncertainty_score":0.9991657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01459506837205889,"score_gpt":0.2616826683462963,"score_spread":0.2470875999742374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}