{"id":"W3216706049","doi":"10.1002/ppul.25779","title":"The use of elexacaftor/tezacaftor/ivacaftor in patients with cystic fibrosis postliver transplant: A case series","year":2021,"lang":"en","type":"article","venue":"Pediatric Pulmonology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Health Services","funders":"","keywords":"Medicine; Cystic fibrosis; Ivacaftor; Liver transplantation; Internal medicine; Gastroenterology; Transplantation; Discontinuation; Liver disease; Lung transplantation; Regimen; Tacrolimus; Cystic fibrosis transmembrane conductance regulator; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001424526,0.0002367497,0.0004947552,0.0002395024,0.0001259272,0.00003077454,0.0001497211,0.0001585062,0.00008398067],"category_scores_gemma":[0.0008617964,0.0001629157,0.00008783249,0.0007911275,0.000271153,0.0002671025,0.00009013677,0.0003843877,0.00001898878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001177556,"about_ca_system_score_gemma":0.0003585874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002428952,"about_ca_topic_score_gemma":0.00008172601,"domain_scores_codex":[0.9977887,0.0002121119,0.0005116629,0.0004377044,0.000419944,0.0006298585],"domain_scores_gemma":[0.9976547,0.001102487,0.0001505119,0.0005355693,0.0003798325,0.0001768448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00490815,0.0004202388,0.986211,0.0002672809,0.00007645673,0.004766294,0.00004616471,0.00003232604,0.0005628342,0.00007129962,0.0004673779,0.002170563],"study_design_scores_gemma":[0.00365507,0.001916974,0.9801309,0.00007222104,0.0002908134,0.00338606,0.000129203,0.00008757158,0.0005396261,0.00006586153,0.009450004,0.0002757637],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969629,0.001975021,0.00007777927,0.0002011168,0.000033979,0.0004903608,0.000185903,0.00003377287,0.00003916711],"genre_scores_gemma":[0.994919,0.0008846907,0.003461254,0.00005490835,0.0001200303,0.00005816557,0.00008104236,0.0000357081,0.0003852131],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008982627,"threshold_uncertainty_score":0.664351,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01384648451584807,"score_gpt":0.2460543863721874,"score_spread":0.2322079018563393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}