{"id":"W3216737886","doi":"10.1016/j.ijbiomac.2021.11.165","title":"Lactoferrin modified by hypohalous acids: Partial loss in activation of human neutrophils","year":2021,"lang":"en","type":"article","venue":"International Journal of Biological Macromolecules","topic":"Infant Nutrition and Health","field":"Nursing","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Russian Science Foundation; Russian Foundation for Basic Research; Belarusian Republican Foundation for Fundamental Research","keywords":"Respiratory burst; Lactoferrin; Myeloperoxidase; Biochemistry; Chemistry; Neutrophil extracellular traps; Azurophilic granule; N-Formylmethionine leucyl-phenylalanine; Granulocyte; Extracellular; Intracellular; Glycoprotein; Concanavalin A; Hypochlorous acid; Inflammation; Biology; Neutrophile; In vitro; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001804783,0.0002431457,0.0002431362,0.00009540454,0.0001240128,0.0001661682,0.0001920967,0.0004192491,0.00120545],"category_scores_gemma":[0.0002344135,0.0001129036,0.0002321866,0.0001028917,0.0002119662,0.0001949363,0.0001805819,0.0003753627,0.0001840702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001048316,"about_ca_system_score_gemma":0.0001171191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006425229,"about_ca_topic_score_gemma":0.0003031979,"domain_scores_codex":[0.9998509,0.00004222473,0.00001106765,0.00002061487,0.00002445878,0.00005074734],"domain_scores_gemma":[0.9999298,0.00001820292,0.00001458467,0.00001434774,0.000008607318,0.00001448534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003360768,0.0000665812,0.0009999103,0.00005193332,0.00001933393,0.0003999939,0.00005384233,0.00006315159,0.9913082,0.00006774538,0.0000539497,0.003554618],"study_design_scores_gemma":[0.00007801296,0.001514818,0.02162525,0.000008611944,0.00005410509,0.002054936,0.00008421275,0.0004341591,0.9725785,0.00006358026,0.001497952,0.000005852925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975325,0.00155575,0.0004977298,0.00004982895,0.00001068452,0.00001264913,0.00007032097,0.000008555809,0.0002620277],"genre_scores_gemma":[0.9987649,0.0003229083,0.0001775607,0.00003348404,0.000005063982,0.00001005642,0.0001348804,0.000002829637,0.0005482666],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00120545,"threshold_uncertainty_score":0.004032612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03924417950127807,"score_gpt":0.3343570834729914,"score_spread":0.2951129039717133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}