{"id":"W3216822205","doi":"10.1161/circ.144.suppl_1.13262","title":"Abstract 13262: Improved Rabbit Model of Calcific Aortic Valve Disease Induces Severe Medial Calcification and Stenosis Equivalent to Human Disease","year":2021,"lang":"en","type":"article","venue":"Circulation","topic":"Cardiac Valve Diseases and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Medicine; Calcification; Osteopontin; Aortic valve; Pathology; Stenosis; Aortic valve stenosis; Osteocalcin; Ex vivo; Alkaline phosphatase; Vitamin D and neurology; Internal medicine; In vivo; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001095001,0.0009189537,0.00119683,0.001018509,0.0004048657,0.0006735361,0.0005075872,0.001171032,0.003800193],"category_scores_gemma":[0.0004087803,0.000485945,0.000660192,0.0005155381,0.0007660376,0.0005731469,0.0004642986,0.001248764,0.001674475],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003935382,"about_ca_system_score_gemma":0.0003904892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004128875,"about_ca_topic_score_gemma":0.0005877953,"domain_scores_codex":[0.9989145,0.0001734626,0.0002037666,0.0002769762,0.0003018034,0.0001296301],"domain_scores_gemma":[0.9992931,0.0000715833,0.0001890281,0.0001770864,0.00007483565,0.0001943434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001394619,0.0005338892,0.0003546303,0.00009772445,0.00001532056,0.00027087,0.00004642777,0.0000373639,0.9955028,0.000191536,0.0001119765,0.001442885],"study_design_scores_gemma":[0.001018251,0.01998466,0.01105916,0.00008108903,0.0001899847,0.006926817,0.0001267792,0.001502048,0.943627,0.0003169588,0.01512851,0.00003870004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9839453,0.00241087,0.007668093,0.0003412064,0.000225188,0.0003135915,0.0009622475,0.0003001752,0.003833374],"genre_scores_gemma":[0.9619594,0.002177587,0.01276611,0.0003980483,0.0001198849,0.0008151726,0.002853464,0.0001626589,0.01874782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003800193,"threshold_uncertainty_score":0.0127129,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04377608813657657,"score_gpt":0.3427788512554144,"score_spread":0.2990027631188378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}