{"id":"W3216861995","doi":"10.1038/s41409-021-01527-z","title":"A second autologous hematopoietic cell transplantation is a safe and effective salvage therapy in select relapsed or refractory AL amyloidosis patients","year":2021,"lang":"en","type":"letter","venue":"Bone Marrow Transplantation","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Medicine; Salvage therapy; Hematopoietic cell; Refractory (planetary science); Surgery; Transplantation; Amyloidosis; Hematopoietic stem cell transplantation; AL amyloidosis; Oncology; Chemotherapy; Stem cell; Haematopoiesis; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001779517,0.0007611338,0.0007732291,0.0002904052,0.0001265394,0.00007349307,0.0001766856,0.001225346,0.0001994286],"category_scores_gemma":[0.00002188021,0.0007127763,0.00025455,0.0002534068,0.0001014239,0.00002994735,0.00001836767,0.0007420839,0.0000143616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001329373,"about_ca_system_score_gemma":0.00017914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009774206,"about_ca_topic_score_gemma":0.0004481596,"domain_scores_codex":[0.9965304,0.0005850003,0.0006849,0.001234022,0.000396795,0.000568842],"domain_scores_gemma":[0.9987258,0.0002752715,0.0003739935,0.0004178776,0.0001161296,0.00009097887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01328235,0.002878139,0.1908657,0.01080549,0.002324786,0.007340671,0.01393855,0.00003035561,0.3420339,0.000004099657,0.3937645,0.02273143],"study_design_scores_gemma":[0.03076974,0.005827852,0.3158372,0.001217376,0.001499592,0.000669637,0.0001757801,0.00002000132,0.5511066,0.00004704982,0.08950095,0.003328208],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841103,0.002067823,0.0001481445,0.009899145,0.0002700357,0.001905697,0.001241978,0.00004910593,0.0003077856],"genre_scores_gemma":[0.856866,0.02389892,0.0005261403,0.1007024,0.0002350202,0.001023113,0.01560894,0.0001963495,0.000943103],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3042636,"threshold_uncertainty_score":0.9995323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007254229749297072,"score_gpt":0.2312532568104828,"score_spread":0.2239990270611857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}