{"id":"W3216961541","doi":"10.3389/falgy.2021.774902","title":"Proteomics Profiling to Distinguish DOCK8 Deficiency From Atopic Dermatitis","year":2021,"lang":"en","type":"article","venue":"Frontiers in Allergy","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Atopic dermatitis; Proteomics; Haptoglobin; Fold change; Immunology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001390809,0.0002524343,0.0002645936,0.000618139,0.0001134978,0.000308865,0.0001017467,0.0002525361,0.0004467843],"category_scores_gemma":[0.0002357215,0.00009590888,0.000186501,0.0003086216,0.0001085499,0.0001417833,0.0002423814,0.0002123675,0.0001117581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001222759,"about_ca_system_score_gemma":0.00006860882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002978877,"about_ca_topic_score_gemma":0.0004332988,"domain_scores_codex":[0.9998804,0.00001695028,0.00001376976,0.00004289458,0.00002752916,0.00001831796],"domain_scores_gemma":[0.9999257,0.00001835485,0.000022217,0.000005914356,0.00001411339,0.00001377676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007994398,0.00004194099,0.0265542,0.0001159601,0.00004613237,0.0003262749,0.00006424041,0.0001312562,0.9647714,0.0000464652,0.00008779878,0.007014912],"study_design_scores_gemma":[0.00005317968,0.0006692199,0.6662217,0.0000400638,0.0001364254,0.003483304,0.0002774461,0.005978205,0.3201753,0.0004424695,0.002502013,0.00002072831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971833,0.0008201568,0.001320708,0.00002151047,0.000008157914,0.0000161706,0.0003604506,0.00002092854,0.0002486337],"genre_scores_gemma":[0.9962993,0.0004324125,0.002263637,0.00004817668,0.000005071203,0.00002168968,0.0006018331,0.000006536279,0.0003212605],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000618139,"threshold_uncertainty_score":0.001494706,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006799211848757838,"score_gpt":0.2093341886099425,"score_spread":0.2025349767611847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}