{"id":"W3217044600","doi":"10.1007/s12017-021-08696-6","title":"Exosomes Derived Neuronal Markers: Immunoaffinity Isolation and Characterization","year":2021,"lang":"en","type":"article","venue":"NeuroMolecular Medicine","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Microvesicles; Western blot; Flow cytometry; Exosome; CD63; Molecular biology; Blot; Biology; Cell biology; Chemistry; microRNA; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003225432,0.0003624976,0.0003435922,0.0003682056,0.0004226642,0.0007765879,0.0003024865,0.0004547304,0.0009404608],"category_scores_gemma":[0.0005862357,0.0001611387,0.0002989088,0.000310324,0.0002572293,0.000517448,0.0007522764,0.0007743329,0.001217489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003307276,"about_ca_system_score_gemma":0.0003434891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003034981,"about_ca_topic_score_gemma":0.0006588802,"domain_scores_codex":[0.9996988,0.00005203475,0.00002921555,0.00005292091,0.00009070298,0.00007643057],"domain_scores_gemma":[0.9997851,0.00005816764,0.00002598487,0.00003773705,0.0000631314,0.00002980498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009829149,0.00005858365,0.0005438764,0.00007421235,0.00001168535,0.0001342924,0.00007672534,0.00008301337,0.9904768,0.001318825,0.0002215574,0.0069022],"study_design_scores_gemma":[0.00001251771,0.00008050524,0.003871443,0.00003206323,0.0000198102,0.0007008816,0.00007657879,0.001022791,0.9813456,0.0006154074,0.01221166,0.00001080814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8698143,0.008093612,0.1116528,0.000827995,0.0002380187,0.0004018594,0.001196108,0.0002140287,0.007561286],"genre_scores_gemma":[0.931913,0.007843445,0.0439339,0.0004101864,0.0001010458,0.0004775989,0.003036303,0.0001824607,0.01210201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009404608,"threshold_uncertainty_score":0.003146172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008713497838823508,"score_gpt":0.2292989866438004,"score_spread":0.2205854888049769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}