{"id":"W3217044600","doi":"10.1007/s12017-021-08696-6","title":"Exosomes Derived Neuronal Markers: Immunoaffinity Isolation and Characterization","year":2021,"lang":"en","type":"article","venue":"NeuroMolecular Medicine","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Microvesicles; Western blot; Flow cytometry; Exosome; CD63; Molecular biology; Blot; Biology; Cell biology; Chemistry; microRNA; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001052515,0.0001733592,0.0001574291,0.00004072041,0.00008360803,0.00002270499,0.0001071594,0.00009419596,0.000115354],"category_scores_gemma":[0.0004428011,0.0001778429,0.00004859089,0.0001260097,0.000140226,0.000008452762,0.0001397337,0.0001130199,0.000005507232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006404147,"about_ca_system_score_gemma":0.00006403169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001599375,"about_ca_topic_score_gemma":0.000001295045,"domain_scores_codex":[0.9987137,0.0002117009,0.000227549,0.000452168,0.0002064347,0.0001884299],"domain_scores_gemma":[0.9992237,0.00001771124,0.0000887886,0.0004176765,0.0001213218,0.0001307723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007359294,0.00006285182,0.001063678,0.00002905516,0.0000312561,0.0001398109,0.00002665536,0.000001761205,0.9956443,0.00004490661,0.0001106302,0.002771551],"study_design_scores_gemma":[0.001261345,0.0003683891,0.1167471,0.00004761064,0.00008513973,0.0002082762,0.00004172937,0.0003602575,0.8740904,0.00006066114,0.006488532,0.0002406001],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909338,0.00145994,0.005743124,0.0009569483,0.0001993443,0.0001373233,0.00001028733,0.00002360416,0.0005356402],"genre_scores_gemma":[0.9956084,0.0006213707,0.0003833397,0.001899019,0.0002450438,0.00001056965,0.0009344012,0.00003717784,0.0002606634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1215539,"threshold_uncertainty_score":0.7252224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008713497838823508,"score_gpt":0.2292989866438004,"score_spread":0.2205854888049769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}