{"id":"W3217283101","doi":"10.3390/ijms222312634","title":"Myelin Quantification in White Matter Pathology of Progressive Multiple Sclerosis Post-Mortem Brain Samples: A New Approach for Quantifying Remyelination","year":2021,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Remyelination; Myelin; Multiple sclerosis; White matter; Luxol fast blue stain; Pathology; Brain tissue; Medicine; Biology; Central nervous system; Magnetic resonance imaging; Neuroscience; Anatomy; Radiology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003070296,0.00065027,0.0004728037,0.002536547,0.0004116603,0.0006719125,0.0005284051,0.0006655371,0.0005703309],"category_scores_gemma":[0.002830454,0.0003978244,0.0004096893,0.0009684238,0.0006943839,0.0008257893,0.0008308902,0.0006018147,0.0002872975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003536005,"about_ca_system_score_gemma":0.000392153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007229535,"about_ca_topic_score_gemma":0.001463752,"domain_scores_codex":[0.9978193,0.0005054626,0.0002355462,0.0006555191,0.0007084351,0.00007571046],"domain_scores_gemma":[0.998036,0.0003481156,0.0006155153,0.0003221668,0.0006133654,0.00006501208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002166679,0.00005150832,0.007442139,0.0004103859,0.0001306325,0.00008685869,0.0004482117,0.0006874463,0.9531596,0.0004891569,0.0001255178,0.03675186],"study_design_scores_gemma":[0.00003788126,0.00149125,0.1532948,0.0001846365,0.0004754763,0.002172505,0.0003801391,0.02056434,0.8117137,0.00153053,0.008009069,0.0001456846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5980418,0.006146024,0.3922799,0.00007464871,0.00009931367,0.0003306603,0.0006683351,0.0008261601,0.001533204],"genre_scores_gemma":[0.6074783,0.002562461,0.3867481,0.00006630613,0.00005257506,0.0006457891,0.0006684772,0.000197657,0.001580322],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003070296,"threshold_uncertainty_score":0.01623744,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1722600749896784,"score_gpt":0.3933787121436592,"score_spread":0.2211186371539808,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}