{"id":"W3217399084","doi":"10.1002/1873-3468.14243","title":"PACS‐1 contains distinct motifs for nuclear‐cytoplasmic transport and interacts with the RNA‐binding protein PTBP1 in the nucleus and cytosol","year":2021,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Nuclear transport; Importin; Nuclear localization sequence; Nuclear export signal; NLS; Nuclear protein; Nucleoporin; Polypyrimidine tract-binding protein; Cell biology; Nuclear pore; RNA-binding protein; RNA; Cell nucleus; Cytoplasm; Cytosol; Transport protein; Ran; Protein targeting; Biology; Heterogeneous ribonucleoprotein particle; Biochemistry; Gene; Transcription factor; Membrane protein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001096097,0.0003370415,0.0002955156,0.0001556338,0.0004032222,0.0003896965,0.0001920879,0.0003155822,0.002071982],"category_scores_gemma":[0.0001984506,0.0001431783,0.0002636834,0.0001364979,0.0003130805,0.0002783715,0.0001888327,0.0005065319,0.0009867122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005036106,"about_ca_system_score_gemma":0.0003002961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004374933,"about_ca_topic_score_gemma":0.0008201516,"domain_scores_codex":[0.9999156,0.00001777182,0.000006784364,0.00002475438,0.00002232739,0.00001272835],"domain_scores_gemma":[0.9998821,0.00002649251,0.0000394155,0.0000118405,0.000009931908,0.00003023089],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008184018,0.00001414948,0.0009313654,0.00005205483,0.000005855951,0.0003372593,0.00002676432,0.0001145884,0.9964773,0.0003623014,0.00008235983,0.001514158],"study_design_scores_gemma":[0.00003358187,0.0003109803,0.03909846,0.00001939056,0.00004284921,0.006474075,0.0000958111,0.002746409,0.9373029,0.0006985416,0.0131484,0.00002858415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937074,0.001724687,0.002670027,0.0001961053,0.00002343534,0.00001200884,0.000191469,0.00006708809,0.001407773],"genre_scores_gemma":[0.9919301,0.0005623692,0.004177866,0.00007625311,0.0000201548,0.0000222261,0.000794736,0.00002546617,0.002390807],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002071982,"threshold_uncertainty_score":0.006931424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005138669789885439,"score_gpt":0.1925018939346287,"score_spread":0.1873632241447433,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}