{"id":"W3217399084","doi":"10.1002/1873-3468.14243","title":"PACS‐1 contains distinct motifs for nuclear‐cytoplasmic transport and interacts with the RNA‐binding protein PTBP1 in the nucleus and cytosol","year":2021,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Nuclear transport; Importin; Nuclear localization sequence; Nuclear export signal; NLS; Nuclear protein; Nucleoporin; Polypyrimidine tract-binding protein; Cell biology; Nuclear pore; RNA-binding protein; RNA; Cell nucleus; Cytoplasm; Cytosol; Transport protein; Ran; Protein targeting; Biology; Heterogeneous ribonucleoprotein particle; Biochemistry; Gene; Transcription factor; Membrane protein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009432813,0.0001092603,0.00009075338,0.00001437473,0.0001295485,0.00005246242,0.00007841814,0.00005135677,0.000005628084],"category_scores_gemma":[0.00001723577,0.00006536279,0.00003136808,0.00004467863,0.00008128252,0.00000705587,0.00002287695,0.0001124107,6.705671e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008694955,"about_ca_system_score_gemma":0.00001168408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001641579,"about_ca_topic_score_gemma":0.0002302665,"domain_scores_codex":[0.9994309,0.00003996341,0.00008706959,0.0002258457,0.00006369021,0.0001525336],"domain_scores_gemma":[0.999741,0.00001789704,0.00003940107,0.0001603843,0.00001595603,0.00002532787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002649136,0.00001487223,0.002736501,0.00002941228,0.00004277613,0.0000323618,0.0008444052,0.000005423065,0.9936544,0.000126651,0.0008413084,0.001406919],"study_design_scores_gemma":[0.009048222,0.002313298,0.3121683,0.0003414567,0.0003505406,0.001287895,0.01055664,0.0003111272,0.3349654,0.0001591296,0.3270166,0.001481343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930829,0.00003580351,0.0002866228,0.006039716,0.00004302025,0.0003194626,0.00001892706,0.000005933982,0.0001675648],"genre_scores_gemma":[0.9971611,0.000008138656,0.0002062146,0.00237134,0.00009126017,0.00001882585,0.00004733509,0.00002070109,0.00007506994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.658689,"threshold_uncertainty_score":0.2665417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005138669789885439,"score_gpt":0.1925018939346287,"score_spread":0.1873632241447433,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}