{"id":"W3217461285","doi":"10.3389/fcvm.2021.768481","title":"Endothelial Cell CD36 Reduces Atherosclerosis and Controls Systemic Metabolism","year":2021,"lang":"en","type":"article","venue":"Frontiers in Cardiovascular Medicine","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"University of Alberta; Faculty of Medicine and Dentistry, University of Alberta; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"CD36; Insulin resistance; Fatty acid; Internal medicine; Endocrinology; Foam cell; Lipid metabolism; Metabolic syndrome; Dyslipidemia; Endothelium; Medicine; Biology; Receptor; Lipoprotein; Diabetes mellitus; Cholesterol; Insulin; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000215908,0.0003265624,0.0006195274,0.0002729628,0.000184978,0.0003988409,0.000252422,0.0004286042,0.001665222],"category_scores_gemma":[0.0002378604,0.0001370111,0.0002355642,0.000209524,0.0002962179,0.0002734337,0.0003218834,0.0008907868,0.0003664744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001858435,"about_ca_system_score_gemma":0.0002454083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006272568,"about_ca_topic_score_gemma":0.0007452396,"domain_scores_codex":[0.9997873,0.00003794576,0.00001895507,0.00004124138,0.00005530708,0.00005933018],"domain_scores_gemma":[0.9997815,0.00001355625,0.00005884882,0.00003463317,0.00002985922,0.00008149161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002314201,0.0002369796,0.0008608932,0.0001324107,0.00003099886,0.00008104329,0.00002912557,0.00009824886,0.9843532,0.0003029662,0.0003317313,0.01122811],"study_design_scores_gemma":[0.0003863804,0.003442883,0.02760202,0.00006936026,0.000248856,0.0009873263,0.0001404893,0.001731413,0.9468328,0.0006488476,0.01788282,0.00002693107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863291,0.006275476,0.003781434,0.000691496,0.0001103662,0.00003507746,0.0002992358,0.0003212111,0.00215649],"genre_scores_gemma":[0.9872518,0.00384976,0.003246489,0.0002307544,0.00005526826,0.00004317448,0.0003407205,0.00005751485,0.004924595],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001665222,"threshold_uncertainty_score":0.005570769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00651901286566264,"score_gpt":0.203644517271194,"score_spread":0.1971255044055313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}