{"id":"W3217461285","doi":"10.3389/fcvm.2021.768481","title":"Endothelial Cell CD36 Reduces Atherosclerosis and Controls Systemic Metabolism","year":2021,"lang":"en","type":"article","venue":"Frontiers in Cardiovascular Medicine","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"University of Alberta; Faculty of Medicine and Dentistry, University of Alberta; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"CD36; Insulin resistance; Fatty acid; Internal medicine; Endocrinology; Foam cell; Lipid metabolism; Metabolic syndrome; Dyslipidemia; Endothelium; Medicine; Biology; Receptor; Lipoprotein; Diabetes mellitus; Cholesterol; Insulin; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006646606,0.0002811663,0.0008391382,0.0001106758,0.000068955,0.00002053275,0.0001821704,0.0002693619,0.00001509139],"category_scores_gemma":[0.0002293706,0.0002471457,0.0003108814,0.0002236492,0.0002149631,0.000008881648,0.0001032256,0.0002132922,0.000002496737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004313517,"about_ca_system_score_gemma":0.0001101026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003044823,"about_ca_topic_score_gemma":0.000001944674,"domain_scores_codex":[0.9978656,0.000372233,0.0003520368,0.0006720914,0.0003680761,0.0003699217],"domain_scores_gemma":[0.9990241,0.00001423691,0.00007682439,0.0006062606,0.0001196538,0.0001589508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005850268,0.00003458991,0.009159581,0.00006303159,0.0009445482,0.00001901466,0.0001826486,0.00007560637,0.9822257,0.000004530116,0.002679293,0.004552982],"study_design_scores_gemma":[0.004731217,0.00009015794,0.001907786,0.0001341384,0.000330449,0.0001295102,0.001091619,0.00003111989,0.9216183,0.0000229416,0.06958278,0.0003299988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7022281,0.2902273,0.004554353,0.0001539015,0.00184941,0.0003072734,0.00002583665,0.00002141092,0.0006323978],"genre_scores_gemma":[0.9865363,0.01019384,0.001524278,0.0002314643,0.001003345,0.00007415556,0.00007051881,0.00005130504,0.0003147698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2843082,"threshold_uncertainty_score":0.9999981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00651901286566264,"score_gpt":0.203644517271194,"score_spread":0.1971255044055313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}