{"id":"W3217659172","doi":"10.1182/blood-2021-147827","title":"Tagraxofusp (SL-401) in Patients with Chronic Myelomonocytic Leukemia (CMML): Updated Results of an Ongoing Phase 1/2 Trial","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Chronic myelomonocytic leukemia; Medicine; Internal medicine; Oncology; Bone marrow; Myelodysplastic syndromes","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0024356,0.0005637489,0.001088795,0.0003140455,0.0001678327,0.0009581891,0.0004678281,0.000673705,0.002052063],"category_scores_gemma":[0.001564299,0.0001770562,0.001091796,0.0004080299,0.0002874797,0.0006778784,0.0002414689,0.00134528,0.000315492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006693923,"about_ca_system_score_gemma":0.0006548685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005319709,"about_ca_topic_score_gemma":0.002067758,"domain_scores_codex":[0.999549,0.0001934858,0.0000409551,0.00005655454,0.00008519137,0.00007473962],"domain_scores_gemma":[0.9991048,0.0002530141,0.0002995023,0.00005905459,0.0001050408,0.0001784706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1936473,0.005411097,0.02418403,0.004880395,0.006681711,0.0004922443,0.0003443903,0.003868201,0.03482445,0.000695905,0.02331309,0.7016572],"study_design_scores_gemma":[0.4059034,0.3001135,0.1596046,0.001869015,0.01668103,0.003857299,0.0003080427,0.005196028,0.01386194,0.002288412,0.09010429,0.0002124999],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9042162,0.07498075,0.001395434,0.003478742,0.0004479309,0.001497948,0.006571493,0.0002493389,0.007162013],"genre_scores_gemma":[0.9499912,0.02828174,0.002380497,0.004154675,0.0004492602,0.001360437,0.0107522,0.00005090248,0.002579054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0024356,"threshold_uncertainty_score":0.0128808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0155453950591511,"score_gpt":0.293888911158437,"score_spread":0.2783435160992859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}