{"id":"W3217694711","doi":"10.1101/2021.11.29.466909","title":"The HUSH complex controls brain architecture and protocadherin fidelity","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Protocadherin; Biology; Neuroscience; Gene silencing; Cell biology; Gene; Cadherin; Genetics; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007004642,0.0002279429,0.0001281343,0.0001931417,0.0001649607,0.0003824705,0.0002022976,0.0001826983,0.0009902394],"category_scores_gemma":[0.0001144627,0.0001333476,0.00008753088,0.00006842378,0.0002456846,0.000145297,0.0004366975,0.0002379055,0.0003365696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004220701,"about_ca_system_score_gemma":0.000173103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005259913,"about_ca_topic_score_gemma":0.0008421527,"domain_scores_codex":[0.9998901,0.000009226314,0.000005635884,0.00003339974,0.00003601612,0.00002562027],"domain_scores_gemma":[0.9998767,0.00001365137,0.00004424131,0.00001306558,0.00001146981,0.00004088797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004287256,0.000003116172,0.0004613002,0.00000686848,0.000003275623,0.00002548207,0.000008445892,0.00006061358,0.9983841,0.0002023374,0.0000301242,0.0007713949],"study_design_scores_gemma":[0.000009030965,0.00004652568,0.01500691,0.000003068657,0.000007910018,0.0001520344,0.0000322136,0.002994506,0.9796849,0.0002119842,0.001844854,0.000006084402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959538,0.0004265029,0.002492833,0.00003122585,0.0000119023,0.000005486921,0.0001529403,0.00009289968,0.0008324301],"genre_scores_gemma":[0.9980909,0.00008369971,0.00052053,0.000009659302,0.000002481119,0.000004722559,0.0001175525,0.00001510858,0.001155264],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009902394,"threshold_uncertainty_score":0.003312707,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01243006912270575,"score_gpt":0.2324800127832871,"score_spread":0.2200499436605814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}