{"id":"W33485233","doi":"10.1111/j.1538-7836.2012.04716.x","title":"Diannexin, an annexin A5 homodimer, binds phosphatidylserine with high affinity and is a potent inhibitor of platelet‐mediated events during thrombus formation","year":2012,"lang":"en","type":"article","venue":"Journal of Thrombosis and Haemostasis","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"Thrombosis and Atherosclerosis Research Institute; SickKids Foundation; Hospital for Sick Children; McMaster University; University of Toronto","funders":"","keywords":"Phosphatidylserine; Platelet; Annexin A5; Platelet activation; Chemistry; Annexin; Thrombus; Fibrin; Thrombin; Hemostasis; Microvesicle; Prothrombinase; Flow cytometry; Coagulation; Biophysics; Molecular biology; In vitro; Cell biology; Biochemistry; Immunology; Internal medicine; Medicine; Phospholipid; Biology; Microvesicles","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001744259,0.0002270401,0.0002175459,0.0002564682,0.0001965922,0.0002197385,0.0002363683,0.0003820167,0.001305553],"category_scores_gemma":[0.0001831852,0.0001759236,0.0001167268,0.0001660109,0.0001599674,0.0001858605,0.0001691261,0.0004588044,0.0003166871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004025842,"about_ca_system_score_gemma":0.0001757228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005103881,"about_ca_topic_score_gemma":0.001117915,"domain_scores_codex":[0.9998752,0.00002446759,0.000008548312,0.00002012545,0.00003901201,0.00003260176],"domain_scores_gemma":[0.9999093,0.00002971805,0.00001561356,0.000009372494,0.000006037226,0.00002987055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000229333,0.00003811162,0.0001509336,0.00002464744,0.000008016365,0.00004327543,0.000007989012,0.00003707259,0.9971169,0.0001186493,0.0001256895,0.002099536],"study_design_scores_gemma":[0.00005607671,0.0003261837,0.003559531,0.000002689291,0.00001039664,0.0005093298,0.00001012561,0.000919064,0.9916011,0.00006162665,0.00294036,0.000003566522],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874802,0.004656732,0.004421293,0.0002822999,0.00005925165,0.00005427576,0.0001841438,0.000101366,0.002760435],"genre_scores_gemma":[0.9934601,0.001082464,0.002049424,0.0000735658,0.00001779165,0.00002420278,0.0004595443,0.00001023873,0.002822728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001305553,"threshold_uncertainty_score":0.00436753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02215890253962684,"score_gpt":0.2621502033102457,"score_spread":0.2399913007706189,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}