{"id":"W336810645","doi":"10.1023/a:1012800813662","title":"Cytotoxic and apoptotic effects of cobalt and chromium ions on J774 macrophages – Implication of caspase-3 in the apoptotic pathway","year":2001,"lang":"en","type":"article","venue":"Journal of Materials Science Materials in Medicine","topic":"Trace Elements in Health","field":"Nursing","cited_by":62,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Orthopaedic Foundation; McGill University","keywords":"Apoptosis; DNA fragmentation; Poly ADP ribose polymerase; Trypan blue; Cytotoxic T cell; Molecular biology; Chemistry; Fragmentation (computing); DNA damage; In vitro; DNA; Caspase; Caspase 3; Incubation; Programmed cell death; Biochemistry; Biology; Polymerase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006989608,0.0001849455,0.0007695841,0.0005872326,0.00009794987,0.00004796432,0.0004228394,0.00007361248,0.00004293678],"category_scores_gemma":[0.001412294,0.0001158358,0.00001642004,0.000527443,0.0008942679,0.0002416407,0.00005882962,0.0001273582,9.194541e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001319148,"about_ca_system_score_gemma":0.00008696471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002268658,"about_ca_topic_score_gemma":0.00001376378,"domain_scores_codex":[0.99673,0.0005697586,0.00139721,0.000241425,0.0006965958,0.0003650334],"domain_scores_gemma":[0.9977329,0.0006368887,0.001104993,0.0002966904,0.00013168,0.00009678159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003986149,0.0001406714,0.0008334065,0.0006041549,0.000003867015,0.00002799923,0.001465544,0.00001606054,0.9957636,0.0002511182,0.00002206563,0.0004728845],"study_design_scores_gemma":[0.001600994,0.001729766,0.1463013,0.001555714,0.00002942188,0.0002621812,0.0006015651,0.000003473677,0.847259,0.000571181,0.000008145057,0.00007718723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950391,0.0002768884,0.000008736408,0.002022017,0.001972592,0.0006408988,0.00001503184,0.000004798031,0.00001993214],"genre_scores_gemma":[0.9987509,0.0003944072,0.0003552882,0.0002230051,0.0002491496,0.0000111521,0.000001402881,0.00001324458,0.000001500429],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1485046,"threshold_uncertainty_score":0.4723645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01671609156953368,"score_gpt":0.3220002954085815,"score_spread":0.3052842038390479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}