{"id":"W337536524","doi":"10.1023/a:1025544309616","title":"Metabolism, not autoxidation, plays a role in α-oxoaldehyde- and reducing sugar-induced erythrocyte GSH depletion: Relevance for diabetes mellitus","year":2003,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Methylglyoxal; Glutathione; Chemistry; Biochemistry; Pentose phosphate pathway; Lactoylglutathione lyase; Metabolism; Xylitol; Deoxyribose; Glycolysis; Enzyme; Fermentation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002421582,0.0002904794,0.00030068,0.0001551693,0.0001952122,0.0003757012,0.0002282275,0.0004378686,0.001078595],"category_scores_gemma":[0.0001983037,0.0001486164,0.000145579,0.0001287364,0.0002746298,0.0005078398,0.0001898611,0.0004618209,0.0002196026],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000207763,"about_ca_system_score_gemma":0.0001364791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002746463,"about_ca_topic_score_gemma":0.0002285311,"domain_scores_codex":[0.9999481,0.00001181802,0.000006185871,0.00001365897,0.00000727095,0.00001289524],"domain_scores_gemma":[0.9998488,0.00002632531,0.00003289177,0.00002928857,0.00002674227,0.00003597341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002845188,0.000120723,0.006769509,0.0001670239,0.00004974555,0.0006927003,0.00007487709,0.0001632662,0.9725971,0.001739272,0.0001930615,0.01458745],"study_design_scores_gemma":[0.0001615232,0.001281212,0.06898131,0.00004530973,0.0001633227,0.003488642,0.0002235515,0.002847538,0.9130265,0.004212744,0.005546352,0.00002195683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9733589,0.01653992,0.007048271,0.0009417495,0.0001864739,0.00002071499,0.0001154705,0.00006190054,0.001726546],"genre_scores_gemma":[0.9926846,0.003865519,0.001535702,0.0001088542,0.00005765976,0.000007065992,0.00008064719,0.000009439377,0.001650498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001078595,"threshold_uncertainty_score":0.003608286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008665315099664802,"score_gpt":0.2473670461199197,"score_spread":0.2387017310202549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}