{"id":"W338592559","doi":"10.1371/journal.pone.0126132","title":"Pandemic Swine-Origin H1N1 Influenza Virus Replicates to Higher Levels and Induces More Fever and Acute Inflammatory Cytokines in Cynomolgus versus Rhesus Monkeys and Can Replicate in Common Marmosets","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada","funders":"National Institute of Allergy and Infectious Diseases; Rijksinstituut voor Volksgezondheid en Milieu; National Institutes of Health","keywords":"Virus; Virology; Biology; Macaque; Immunology; Viral replication; Viral shedding; Influenza A virus; Rhesus macaque; Viral load","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001634614,0.0002339408,0.0002817588,0.0004506615,0.0003608732,0.0003473685,0.00006591881,0.0002341338,0.0015825],"category_scores_gemma":[0.0001969575,0.0001123818,0.0003200379,0.0001635982,0.000255048,0.0002567605,0.000276469,0.0003792334,0.0002390118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002205416,"about_ca_system_score_gemma":0.0001388572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001337869,"about_ca_topic_score_gemma":0.001714098,"domain_scores_codex":[0.9998201,0.00003508078,0.00001615526,0.00005003389,0.0000250777,0.00005359557],"domain_scores_gemma":[0.9999188,0.00001008771,0.00002460564,0.00001090489,0.000008997036,0.00002664847],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000576543,0.0001109216,0.01754153,0.00007929051,0.00004026641,0.000229391,0.0002857349,0.00003039804,0.9785995,0.00007886743,0.00006971214,0.00235786],"study_design_scores_gemma":[0.00003459222,0.002282645,0.8400465,0.00002371883,0.0001047914,0.002625842,0.0009811664,0.0006402482,0.1501944,0.0002221871,0.002824661,0.00001918693],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989353,0.0003685158,0.0001464459,0.00002151951,0.000007158295,0.000008351729,0.0001020521,0.000005106108,0.0004055812],"genre_scores_gemma":[0.9983687,0.0002669338,0.0003296544,0.00004210496,0.0000103555,0.00005700648,0.0003288459,0.000005271225,0.0005911932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0015825,"threshold_uncertainty_score":0.005294025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3002947916066933,"score_gpt":0.3982570213579536,"score_spread":0.09796222975126029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}