{"id":"W338936873","doi":"10.1182/blood.v126.23.908.908","title":"Additional Analyses of a Randomized Phase II Study of Azacitidine Combined with Lenalidomide or with Vorinostat Vs. Azacitidine Monotherapy in Higher-Risk Myelodysplastic Syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML): North American Intergroup Study SWOG S1117","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Lenalidomide; Azacitidine; International Prognostic Scoring System; Internal medicine; Myelodysplastic syndromes; Chronic myelomonocytic leukemia; Oncology; Decitabine; Adverse effect; Clinical endpoint; Phases of clinical research; Gastroenterology; Randomized controlled trial; Multiple myeloma; Clinical trial; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008620099,0.0006943847,0.003422996,0.001077581,0.0001159455,0.000035614,0.0003544852,0.00007500653,0.000657066],"category_scores_gemma":[0.0006584477,0.0004383075,0.0001512175,0.002006454,0.001105855,0.0002458211,0.0002044618,0.0006558419,0.00000379298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006367975,"about_ca_system_score_gemma":0.001967925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002519924,"about_ca_topic_score_gemma":0.005870299,"domain_scores_codex":[0.9947729,0.0008792152,0.001433402,0.0009026151,0.001348872,0.000663045],"domain_scores_gemma":[0.995167,0.001949255,0.001005369,0.0007963296,0.0006077447,0.0004742825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8411875,0.02698293,0.1071919,0.0003734636,0.01163555,0.002731102,0.005110076,0.000696628,0.0009194755,0.00000830899,0.0006988121,0.002464184],"study_design_scores_gemma":[0.7881368,0.1538015,0.04482039,0.0005845467,0.003685394,0.0003043475,0.004162878,0.002381345,0.001543615,0.000008025769,0.00003324121,0.0005378356],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939342,0.0002229844,0.00009900223,0.0000865958,0.00002611059,0.004661752,0.000842415,0.0000710989,0.00005586836],"genre_scores_gemma":[0.9968706,0.0002098063,0.0008351182,0.00003196864,0.0001068641,0.001059844,0.0004699809,0.000111864,0.0003039042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1268186,"threshold_uncertainty_score":0.9998069,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0458846168319952,"score_gpt":0.3269646633340721,"score_spread":0.281080046502077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}