{"id":"W338936873","doi":"10.1182/blood.v126.23.908.908","title":"Additional Analyses of a Randomized Phase II Study of Azacitidine Combined with Lenalidomide or with Vorinostat Vs. Azacitidine Monotherapy in Higher-Risk Myelodysplastic Syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML): North American Intergroup Study SWOG S1117","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Lenalidomide; Azacitidine; International Prognostic Scoring System; Internal medicine; Myelodysplastic syndromes; Chronic myelomonocytic leukemia; Oncology; Decitabine; Adverse effect; Clinical endpoint; Phases of clinical research; Gastroenterology; Randomized controlled trial; Multiple myeloma; Clinical trial; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007060404,0.002316211,0.003333174,0.0006047811,0.0006161721,0.001361815,0.001133973,0.001794123,0.009443963],"category_scores_gemma":[0.005416671,0.0007744971,0.006326496,0.0006976786,0.0009577149,0.001139893,0.0008236804,0.003626186,0.0009018175],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001220857,"about_ca_system_score_gemma":0.002593395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001186952,"about_ca_topic_score_gemma":0.003301377,"domain_scores_codex":[0.9957883,0.002946739,0.0002217383,0.000551738,0.0001765848,0.0003148947],"domain_scores_gemma":[0.9951925,0.001913092,0.0009842215,0.0005986081,0.0003306124,0.0009809184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9769182,0.005371499,0.002770168,0.0002686223,0.006011029,0.00004339829,0.0000402509,0.0004757226,0.00168884,0.00007614814,0.00106517,0.005270862],"study_design_scores_gemma":[0.8785217,0.09972847,0.01140826,0.00003262474,0.006922577,0.0000608081,0.00004776329,0.0008099976,0.0007539772,0.0003086332,0.001380008,0.00002516089],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816703,0.002323549,0.001037165,0.0007419874,0.0004030751,0.006892163,0.0044749,0.0001050873,0.00235188],"genre_scores_gemma":[0.975713,0.0008502385,0.002687846,0.001187728,0.0003961659,0.009298055,0.006565555,0.00005176874,0.003249559],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009443963,"threshold_uncertainty_score":0.03733945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0458846168319952,"score_gpt":0.3269646633340721,"score_spread":0.281080046502077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}