{"id":"W342233364","doi":"10.1089/scd.2014.0013","title":"Connexin31.1 ( <i>Gjb5</i> ) Deficiency Blocks Trophoblast Stem Cell Differentiation and Delays Placental Development","year":2014,"lang":"en","type":"article","venue":"Stem Cells and Development","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft","keywords":"Trophoblast; Biology; Placentation; Stem cell; Placenta; Embryonic stem cell; Cell biology; Cellular differentiation; Spiral artery; Phenotype; Endocrinology; Andrology; Genetics; Fetus; Gene; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002225448,0.0002770182,0.0002285021,0.00005421084,0.0002684054,0.00005257866,0.0001113368,0.0001736082,0.00002028732],"category_scores_gemma":[0.000001404645,0.0002400675,0.00003156654,0.00004421231,0.00007267929,0.00000477496,0.0002334062,0.00008291272,0.00001597661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002775943,"about_ca_system_score_gemma":0.0001126287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005592342,"about_ca_topic_score_gemma":0.00005271252,"domain_scores_codex":[0.9985128,0.00006307488,0.0003648045,0.0005612492,0.0001321196,0.0003659456],"domain_scores_gemma":[0.9994671,0.00002193008,0.0001178941,0.0001774141,0.00005284869,0.0001627828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002231544,0.0002029045,0.01474895,0.0002111901,0.00007889716,0.000005134373,0.001763018,0.00001662533,0.8139009,0.0001586747,0.0009439407,0.1677465],"study_design_scores_gemma":[0.001508522,0.0003209731,0.008831702,0.00002717265,0.00001587508,0.00002523623,0.000622982,0.0001089147,0.7874433,0.000006561301,0.2005336,0.0005551076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930108,0.001288353,0.004076676,0.00002554243,0.0002058053,0.0002205148,0.00000769999,0.00001789155,0.001146732],"genre_scores_gemma":[0.9967548,0.0002244552,0.001468857,0.0002087178,0.00005847905,0.00002790248,0.00006213946,0.00002085241,0.001173799],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1995897,"threshold_uncertainty_score":0.978967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006286517898411568,"score_gpt":0.1789157450178766,"score_spread":0.172629227119465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}